| Objective To explore the relationship between serum B-type natriuretic peptide(BNP), cardiac troponin Ⅰ(cTnⅠ) levels and readmission in elderly patients with chronic heart failure(CHF). Methods A total of 150 elderly CHF patients who visited the Second People's Hospital of Liaocheng from June 2022 to December 2023 were selected as the research subjects. After improvement and discharge, they were followed up for one year and divided into the readmission group and non-readmission group according to whether they were readmitted or not. The general information, serum BNP and cTnⅠ levels were compared between the two groups, logistic regression equation was used to analyze the influencing factors for readmission in elderly CHF patients. Restricted cubic spline model(RCS) was used to analyze the relationship between serum BNP and cTnⅠ levels and readmission in elderly CHF patients. Receiver operating characteristic curve(ROC) was used to analyze the predictive value of serum BNP and cTnⅠ levels for readmission in elderly CHF patients. Results After one year of follow-up after improvement and discharge, there were 6 cases lost to follow-up, 43 cases readmitted, and 101 cases not readmitted among the study subjects, with incidence rates of 29.86%(43/144) and 70.14%(101/144), respectively. The serum BNP, cTnⅠ, creatine kinase(CK), lactate dehydrogenase(LDH), aspartate aminotransferase(AST), and hyperlipidemia in the readmission group were higher than those in the non-readmission group, and the left ventricular ejection fraction(LVEF) was lower than that in the non-readmission group(P<0.05). BNP, cTnⅠ, hyperlipidemia and LVEF are influencing factors for the readmission of elderly CHF patients(P<0.05). After adjusting for other covariates, there was a non-linear relationship(P<0.05) between serum BNP and cTnⅠ levels and readmission of elderly CHF patients. When the serum BNP and cTnⅠ levels were greater than 319.08 pg/mL and 1.18 μg/L, respectively, the risk of readmission in elderly CHF patients continued to increase. When they were greater than 362.47 pg/mL and 1.34 μg/L, the risk of readmission in elderly CHF patients remained unchanged, showing a plateau effect. The AUC predicted by serum BNP and cTnⅠ for readmission in elderly CHF patients was 0.753 and 0.775, respectively, with a combined AUC of 0.910, which was higher than the AUC predicted by single prediction(P<0.05). Conclusion There is a non-linear correlation between serum BNP, cTnⅠ and readmission in elderly CHF patients, and BNP combined with cTnⅠ has a high predictive power in readmission risk assessment. |
