文章摘要
基于潜在剖面分析的老年慢阻肺患者口腔健康相关生活质量及其干预策略研究
Study on OHRQoL and intervention strategies in elderly patients with COPD based on potential profile analysis
投稿时间:2026-03-02  
DOI:10.3969/j.issn.1000-0399.2026.09.014
中文关键词: 慢性阻塞性肺疾病  口腔健康相关生活质量  潜在剖面分析
英文关键词: Chronic obstructive pulmonary disease  Oral health-related quality of life  Latent profile analysis
基金项目:安徽省教育厅重点项目基金(编号:2024AH050737);2025年度安徽医科大学护理学院研究生青苗培育项目(编号:Hlqm12025080)
作者单位E-mail
葛瑶 230032 安徽合肥 安徽医科大学护理学院  
张会 230022 安徽合肥 安徽医科大学第一附属医院护理部
230001 安徽合肥 安徽省公共卫生临床中心护理部 
zhanghui310@fy.ahmu.edu.cn 
仲蕾 230022 安徽合肥 安徽医科大学第一附属医院护理部  
张程程 230022 安徽合肥 安徽医科大学第一附属医院护理部  
杨秀英 230022 安徽合肥 安徽医科大学第一附属医院护理部  
朱凤伊 230032 安徽合肥 安徽医科大学护理学院  
刘梦 230032 安徽合肥 安徽医科大学护理学院  
陈叶俊 230032 安徽合肥 安徽医科大学护理学院  
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中文摘要:
      目的 应用潜在剖面分析识别老年慢性阻塞性肺疾病(COPD)患者口腔健康相关生活质量(OHRQoL)的分型,并分析不同分型的影响因素。方法 采用横断面调查法,以便利抽样法选取2024年4月至2025年5月在安徽医科大学第一附属医院住院的265例老年COPD患者为研究对象,采用一般资料调查问卷、口腔健康影响程度量表(OHIP-14)、社会支持量表(SSRS)、老年人口腔健康知信行问卷、改良Barthel指数(MBI)进行调查。用Mplus 8.3软件构建潜在剖面分析模型。结果 265例COPD患者OHIP-14平均得分(15.00±8.94)分。潜在剖面分析结果示,老年COPD患者OHRQoL可分为3个潜在类别:低症状无损害组、中等症状社交受限组、高症状多维度障碍组,3组的占比分别为52.8%(n=140)、35.1%(n=93)和12.1%(n=32)。单因素分析结果示,3个潜在类别的患者在年龄、文化程度、家庭人均月收入、医保付费类型、户口所在地、天然牙状况、年住院次数、肺功能分级、SSRS、MBI及口腔健康知信行得分上差异具有统计学意义(P<0.05);多元logistic回归分析结果显示,年住院次数、肺功能分级、天然牙状态、SSRS及口腔健康知信行得分是影响患者类别的独立因素。结论 老年COPD患者OHRQoL水平存在明显的异质性,医护人员可根据患者OHRQoL的潜在类别特征实施精准干预,以增强患者OHRQoL水平。
英文摘要:
      Objective To identify the latent profiles of oral health-related quality of life(OHRQoL) in elderly patients with chronic obstructive pulmonary disease(COPD) and to explore the influencing factors of different profiles. Methods A cross-sectional survey was conducted using convenience sampling to select 265 elderly COPD patients hospitalized at the First Affiliated Hospital of Anhui Medical University from April 2024 to May 2025 as the study subjects. The study tools included a general information questionnaire, the Oral Health Impact Profile-14(OHIP-14), the Social Support Rating Scale(SSRS), an Elderly Oral Health Knowledge, Attitude, and Practice(KAP) Questionnaire, and the Modified Barthel Index(MBI). A latent profile analysis(LPA) model was constructed using Mplus 8.3 software. Results The average OHIP-14 score of the 265 COPD patients was 15.00±8.94. Latent profile analysis revealed that the OHRQoL of elderly COPD patients could be classified into three latent categories: a low-symptom group without impairment, a moderate-symptom group with social limitations, and a high-symptom group with multidimensional dysfunction, accounting for 52.8%(n=140),35.1%(n=93),and 12.1%(n=32) respectively. Univariate analysis demonstrated statistically significant differences among the three categories in terms of age, education level, per capita monthly household income, medical insurance payment type, place of residence, natural tooth status, annual hospitalization frequency, pulmonary function classification, SSRS score, MBI score, and oral health KAP scores(P<0.05). Multivariate logistic regression analysis identified annual hospitalization frequency, pulmonary function classification, natural tooth status, SSRS score, and oral health KAP scores as independent predictors influencing the latent category assignments(P<0.05). Conclusion Significant heterogeneity exists in OHRQoL levels among elderly COPD patients. Healthcare providers can implement precision interventions based on the latent profile characteristics of patients' OHRQoL to enhance their overall quality of life.
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