文章摘要
肠结核18例临床分析
Analysis of 18 cases of intestinal tuberculosis diagnosed
投稿时间:2019-01-23  修订日期:2019-09-06
DOI:
中文关键词: 肠结核  诊断  内镜  病理
英文关键词: Intestinal tuberculosis  Diagnosis  Endoscopy  Pathology
基金项目:
作者单位邮编
马晓菡 安徽医科大学第一附属医院 230088
胡乃中* 安徽医科大学第一附属医院 230022
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中文摘要:
      目的 总结分析经肠镜病理确诊肠结核(ITB)患者的临床特点。 方法 回顾性分析安徽医科大学第一附属医院消化内科2017年1月至2018年6月收治的18例经肠镜病理确诊的ITB患者的临床资料,对ITB的临床表现、实验室检查、影像学、肠镜及病理情况等数据进行总结分析。 结果 18例患者中,腹痛16例(88.9%)、腹泻11例(61.1%);结核感染T细胞斑点试验(T-SPOT.TB)阳性率为83.3%(15/18),结核菌素试验(PPD)阳性率为55.6%(10/18);影像学检查示10例(55.6%)患者合并肺结核,肺结核经胸片诊断率为22.2%(4/18),经胸部高分辨CT诊断率为42.9%(6/14);小肠CT(CTE)特征分析显示病灶累及回盲部12例(66.7%),肠壁对称性增厚11例(61.1%),淋巴结环形强化10例(55.6%),腹水7例(38.9%);肠镜显示环形溃疡10例(55.6%)、鼠咬征8例(44.4%)、回盲瓣挛缩呈鱼口状开放4例(22.2%)。18例患者均通过病理确诊,病理组织学抗酸染色阳性率83.3%(15/18),干酪样坏死性肉芽肿检出率44.4%(8/18)。 结论 ITB临床特征缺乏特异性,难以明确诊断,应加强病理组织学检查,同时结合临床表现、实验室检查、影像学检查,以提高诊断水平。
英文摘要:
      Objective To analyze the clinical data of intestinal tuberculosis which was confirmed by pathology,to improve the ability of diagnosis of intestinal tuberculosis. Methods 18 cases of intestinal tuberculosis which was confirmed by pathology admitted to the department of gastroenterology of the first affiliated hospital of anhui medical university from January 2017 to June 2018 were analyzed retrospectively.The laboratory, imaging, endoscopic and pathological features were analyzed,to summarize the characteristics of intestinal tuberculosis and diagnostic experience. Results Among the 18 patients, 16 (88.9%) had abdominal pain and 11 (61.1%) had diarrhea.The positive rate of t-spot.tb and PPD was 83.3% (15/18) and 55.6% (10/18) respectively.Imaging examination showed that 10 cases (55.6%) were complicated with pulmonary tuberculosis. The diagnostic rate of pulmonary tuberculosis was 22.2% (4/18) by chest X-ray, and 42.9% (6/14) by chest high-resolution CT.Analysis of features of small intestine CT (CTE) showed focal involvement in ileocecal area in 12 cases (66.7%), symmetrical thickening of intestinal wall in 11 cases (61.1%), annular enhancement of lymph nodes in 10 cases (55.6%), and ascites in 7 cases (38.9%).Enteroscopy showed annular ulcer in 10 cases (55.6%), rat bite in 8 cases (44.4%), ileocecal contracture in 4 cases (22.2%).All the 18 patients were confirmed by pathology. The positive rate of acid-fast staining by histopathology was 83.3% (15/18), and the detection rate of caseous necrotizing granuloma was 44.4% (8/18). Conclusion Due to the lack of specificity in clinical features of intestinal tuberculosis, emphasis should be put on strengthening histopathology, combining with laboratory and imaging examinations, to improve the level of diagnosis of intestinal tuberculosis.
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