| [Abstract] Objective: To investigate the use of statins lipid-lowering drugs and the compliance rate of low density lipoprotein cholesterol (LDL-C) in patients with coronary heart disease in our hospital, and to explore the risk factors affecting the compliance rate of LDL-C. Methods: 119 patients with coronary heart disease admitted to our hospital from June 2017 to March 2019 were randomly selected by HIS system, and the clinical data on admission were collected for retrospective analysis. For example, gender, age, duration of coronary heart disease, underlying diseases, type of statin taken at home, and examination indicators on admission (LDL-C, total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol, glutamic-pyruvic transaminase), etc. According to whether the LDL-C was lower than 1.80 mmol/L, the ldL-C group was divided into the standard LDL-C group and the non-standard LDL-C group. The general data of patients between the two groups were compared and analyzed by 2 test, and multivariate analysis was conducted by logistic regression analysis. Results: Among 119 patients with coronary heart disease, 92 (77.31%) took statins, 29 (24.37%) took LDL-C < 1.8 mmol/L. Whether OR not to take statins (OR= 0.15, 95%Cl: 0.026-0.853, P=0.032) and history of hypertension (OR=4.420, 95%CL: 1.703-11.472, P=0.002) were independent risk factors for ldL-C level failure at admission in patients with coronary heart disease. When LDL-C reached the standard, TC and TG levels were significantly lower than those of the group without the standard (P < 0.05). Conclusions: The utilization rate of statins for the secondary prevention of CORONARY heart disease is low, and the target rate of blood lipid is low. Individualized lipid regulation intervention should be formulated for patients with coronary heart disease after discharge according to the above two independent risk factors to improve the target rate of blood lipid. |
