文章摘要
米汤和清水鼻饲治疗急性脑损伤高钠血症的临床疗效
Clinical comparative study of nasogastric rice water and pure water in treating patients with hypernatremia caused by acute braininjury
投稿时间:2015-02-20  修订日期:2015-06-05
DOI:10.3969/j.issn.1000-0399.2015.08.016
中文关键词: 高钠血症  鼻饲  米汤  清水  脑损伤,急性
英文关键词: Hypernatremia  Nasogastric gavage  Rice water  Pure water  Brain injury, Acute
基金项目:
作者单位
武道荣 230001 安徽省合肥市第三人民医院(安徽医科大学合肥第三临床学院)急救中心 
宋秋鸣 230001 安徽省合肥市第三人民医院(安徽医科大学合肥第三临床学院)急救中心 
孔翎 230001 安徽省合肥市第三人民医院(安徽医科大学合肥第三临床学院)急救中心 
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中文摘要:
      目的 分别通过米汤、清水鼻饲和静脉输液治疗急性脑损伤高钠血症,比较3种方法纠正重症高钠血症的临床效果。方法 收集44例急性脑损伤的高钠血症患者,分为米汤鼻饲治疗组18例,清水鼻饲治疗组15例,静脉输液对照组11例。比较3组患者出现高钠血症的血钠水平、血钠恢复正常所需时间、肠鸣音恢复所需时间、胃内容物隐血、病死率及米汤和清水鼻饲并发症情况。 结果 米汤组血钠恢复所需时间(88.11±7.14) h,与清水组血钠恢复时间(93.07±8.09) h比较差异无统计学意义(P >0.05),但都短于对照组(179.36±13.51) h(P <0.05);米汤组的肠鸣音恢复时间(32.17±5.78)h短于清水组(90.00±7.93) 及对照组(384.91±35.71) h(P均<0.05);对于胃内容物隐血的发生,清水组多于米汤组,但都少于对照组(P <0.05);米汤组鼻饲的并发症少于清水组(P <0.05),对照组的病死率均高于米汤组和清水组(P <0.05)。 结论 鼻饲是一种简便、安全的纠正高钠血症的治疗方法,使用米汤鼻饲能使患者肠功能较快恢复,且并发症少,值得临床推广应用。
英文摘要:
      Objective To compare the clinical results of three methods treating hypernatremia caused by acute brain injury-nasogastric rice water or pure water, or intravenous infusion-in relieving severe hypernatremia symptom. Methods 44 patients suffering from hypernatremia symptom caused by acute brain injury were divided into three treatment groups:18 patients were treated by nasogastric gavage of rice water,15 patients by nasogastric gavage of pure water, and the other 11 patients by intravenous infusion. The blood sodium levels, recovery time for normal sodium levels and bowel sounds, occult blood in stomach contents, mortality rate and complications caused by nasogastric gavage among the three groups were compared. Results The sodium level recovery time in the rice water group (88.11±7.14) h was not statistically different with that in the pure water group (93.07±8.09) h (P >0.05), but they were shorter than that in the intravenous infusion group (179.36±13.51) h (P <0.05). The bowel sounds recovery time in the rice water group (32.17±5.78) h was shorter than those in the pure water group (90.00±7.93) h and the intravenous infusion group (384.91±35.71) h (P <0.05). The occult blood of stomach contents in the rice water group was more common than the pure water group, but was less than the intravenous infusion group (P <0.05). The complications caused by nasogastric gavage in the rice water group were fewer than the pure water group (P <0.05), and the mortality rate in the intravenous infusion group was higher than the other two groups (P <0.05). Conclusion Nasogastric gavage is a simple and safe therapy to treat hypernatremia, and It is worthy of clinical application to use nasogastric rice water for patients with hypernatremia, which would make their bowel function recovery more faster with less complication.
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