| Objective To observe the assisted effect of dexmedetomidine (Dex) on comfortable anesthesia of ultrasound-guided brachial plexus block in the forearm operation.Methods Sixty patients ever underwent selective forearm operation in our hospital from Mar to Jun 2015 were randomly divided into two groups (each n=30):group D (the study group) and group N (the control group).Patients in group D were administered with Dex (micro-pump infusion with loading dose of 0.7 μg/kg, then with maintenance dose of 0.4 μg/kg/h) at 15 min before the brachial plexus block.All patients then underwent ultrasound-guided supraclavicular brachial plexus block with a 20 mL mixture of 0.375% levobupivacaine+1% lidocaine.The results of MAP, HR, RR, SpO2 and sedation scores (Ramsay scores) at the time of entering operation room (T0), before plexus block (T1), during plexus block (T2), after plexus block (T3), skin incision (T4) and 20 min after the start of surgery (T5) between the two groups were recorded and compared.The VAS scores during anesthesia and at the start of skin incision, the adverse reactions appeared and scores of anesthesia satisfaction were also observed and recorded.Results In comparison with group N, patients in group D showed significantly lower MAP, slower HR and higher Ramsay scores at the time of T1-T5 (all P<0.05).The VAS scores during anesthesia and at the start of skin incision in group D were significantly lower than those in group N (P<0.05), but the scores of anesthesia satisfaction in group D were significantly higher than those in group N (P<0.05).Conclusion For patients undergoing anesthesia and forearm operation, assisted administration of Dex could significantly release their discomfort during the puncture process and their anxiety state during anesthesia, providing more perfect anesthetic effect and hemodynamic stability at the time of skin incision and during the course of anesthesia and operation, so that their anesthesia satisfaction would be higher. |
