| Objective To explore the correlation between perioperative hemorrhage and major adverse cardiovascular events in elderly patients with coronary heart disease one year after PCI.Methods 570 patients with coronary heart disease underwent PCI from January 2013 to December 2014 in our hospital were divided into perioperative hemorrhage group (82 cases) and non-hemorrhage group (488 cases) according to patients with or without perioperative hemorrhage. General information, PCI indicators and adverse cardiovascular events 1 year after PCI of patients in two groups were compared. Cox proportional hazard regression analysis was used to analyze the relationship between perioperative hemorrhage and major adverse cardiovascular events during 1 year after PCI.Results Compared to non-hemorrhage group, patients in perioperative hemorrhage group had older age, higher proportion of BMI≤20, 20~25, lower proportion of preoperative diagnosis of unstable angina pectoris and higher proportion of ST segment elevation myocardial infarction (STEMI), lower hemoglobin (Hb), hematocrit, left ventricular ejection fraction (LVEF) and creatinine clearance rate, lower proportion of transradial approach, higher proportion of application of intravascular ultrasound and intra-aortic balloon pump, lower proportion of aspirin and higher proportion of cilostazol (P<0.05). Compared to non-hemorrhage group, patients in perioperative hemorrhage group had higher rate of cardiac death, death, myocardial infarction and death 1 year after PCI (P<0.05). Cox proportional hazard regression analysis showed that the perioperative period of 2 and above hemorrhage was the independent predictors of major adverse cardiovascular events during the 1 year after PCI (HR=2.394, 95%CI=1.259~4.553, P=0.008).Conclusion Perioperative hemorrhage of grade 2 and above in PCI is an independent risk factor for adverse cardiovascular events in 1 year after operation. |
