| Objective To investigate the imaging and clinicopathological features of minimally invasive adenocarcinom(MIA).Methods A total of 23 MIA cases from Jan. 2016 to Dece. 2016 were selected. The clinical data, radiological and pathological characteristics were retrospectively analyzed. The related literature was reviewed as well. Results 16 of the 23 cases were female and 7 were male. Very few of them were smokers. CT scan revealed the mixed density irregular nodules with solid components in lesions and an average size of 1.2 cm. And the depressing pleura and concentrations could be seen in the edge of the mass. Grossly, masses were circumscribed gray brown and gray white, with diameters from 0.5cm to 2.0cm, and tougher than the normal lung tissues.Light microscopic evaluation showed that the tumor cells were attached to the bronchial wall or the alveolar wall,appearing papillary structure, acinar structure in the minimally invasive lesion, which ranged from 0.2cm to 0.5cm in diameter.Conclusion Usually MIA is small, less than 3cm in diameter, and isolated. Any invasive lesion is less than 0.5cm in diameter, without the interstitial vascular and pleura invasion. |
