| Objective To observe the effectiveness and safety of intracameral injection with triamcinolone acetonide in phacoemulsification and intraocular lens (IOL) implantation in those patients with complicated cataract. Methods 79 cases (79 eyes) of patients with complicated cataract, ever treated in our hospital from Jun 2013 to Jun 2015, were selected and divided into the study group (n=40) and the control group (n=39) by means of random number table. The study group (40 eyes) was given intracameral injection with triamcinolone acetonide (2 mg/0.1 mL) after IOL implantation and sodium hyaluronate replacement, while the control group (39 eyes) was given intracameral injection with 0.1 mL equilibrium liquid. The inflammation and exudation in anterior chamber, change of intraocular pressure (IOP) and count of corneal endothelial cells in the patients of both groups were examined and observed, and the postoperative complications of posterior synechia and IOL anterior membrane in the two groups were followed up for 3 months. Results The inflammation reaction in anterior chamber in the study group was significantly lower than that in the control group at 3, 7, 14 days after operation (χ3d2=18.89, χ7d2=23.75, χ2w2=16.08; P<0.05). There was no significant difference in the postoperative count of corneal endothelial cells between the two groups (F=0.32; P>0.05), and so was difference in the increase of IOP between them (F=3.23; P>0.05). After postoperative follow-up of 3 months, posterior synechia and IOL anterior membrane were found in 5 eyes in the control group and were not found in the study group. Conclusion Application of intracameral injection with triamcinolone acetonide in treatment of complicated cataract could inhibit the postoperative inflammation and exudation in anterior chamber, reduce the occurrence of complications with easy administration and safe and effective therapeutic effects, while affecting IOP and corneal endothelial cells slightly. |
