Objective To explore the clinical efficacy of laparoscopy combined with choledochoscopy in the treatment of those patients with cholecysolithiasis and choledocholithiasis. Methods The clinical data of 68 patients with cholecysolithiasis and choledocholithiasis, ever treated in our hospitals from Jan 2012 to Dec 2015, were retrospectively analyzed. According to the type of operation, 38 patients underwent laparoscopic minimally invasive operation were divided into the laparoscopy group, while other 30 patients treated by conventional open laparotomy were divided into the laparotomy group. The intraoperative blood loss, operative time, intestinal exhaust time, hospitalization days, postoperative complications, together with the white blood cell count (WBC) at 2 days after operation, percent of neutrophils (NEUT%) and levels of C reactive protein (CRP), between the patients of two groups were compared. Results Compared with the laparotomy group, the laparoscopy group had significantly less intraoperative blood loss, shorter intestinal exhaust time and hospitalization days, lower incidences of postoperative wound pain and incision infection (all P<0.05). But there was no significant difference between the laparoscopy group and the laparotomy group in the operative time, postoperative biliary leakage, and bile duct residual calculi (P>0.05). At 2 days after surgery, the NEUT% and CRP in the laparoscopy group were lower than those in the laparotomy group, with significant differences (P<0.05). Conclusion In treatment of cholecysolithiasis with choledocholithiasis, application of laparoscopy combined with choledochoscopy has advantages of less trauma and pain, faster postoperative recovery and definite therapeutic effects, and is worth of clinical promotion. |