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| 经右胸颈胸腹三野清扫食管癌根治术的胸段食管癌患者喉返神经旁淋巴结转移的危险因素分析 |
| Analysis of risk factors for metastases of recurrent laryngeal nerve lymph nodes in patients with thoracic esophageal cancer receivingradical dissectionof tumors and 3-field lymph nodesvia right chest |
| 投稿时间：2017-07-27 |
| DOI：10.3969/j.issn.1000-0399.2017.11.017 |
| 中文关键词: 食管癌 危险因素 喉返神经旁淋巴结 转移 |
| 英文关键词: Esophageal cancer Risk factor Recurrent laryngeal nervelymph nodes Metastasis |
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| 摘要点击次数: 1860 |
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| 中文摘要: |
| 目的 分析经右胸颈胸腹三野清扫食管癌根治术的胸段食管癌患者喉返神经旁淋巴结转移的危险因素。方法 回顾性分析2016年1~12月安徽医科大学第一附属医院收治的166例经右胸颈胸腹三野清扫食管癌根治术的胸段食管癌患者的临床资料,将发生喉返神经旁淋巴结转移患者46例设为观察组,未发生喉返神经旁淋巴结转移患者120例设为对照组,对两组可能影响患者喉返神经旁淋巴结转移的影响因素（性别、肿瘤位置、肿瘤大小、病理类型等）进行单因素分析,对有统计学意义的因素进行多因素logistic回归分析。结果 单因素分析显示,观察组与对照组患者年龄、隆突下淋巴结有无转移、肿瘤分化程度、肿瘤浸润深度（T分期）差异有统计学意义（P<0.05）。logistic多因素回归分析显示,肿瘤分化程度、肿瘤浸润深度与喉返神经旁淋巴结转移有相关关系（P<0.05）。结论 肿瘤分化程度、肿瘤浸润深度（T分期）为喉返神经旁淋巴结转移的独立危险因素。 |
| 英文摘要: |
| Objective To identify the risk factors for metastases of recurrent laryngeal nerve lymph nodes in thosepatients with thoracic esophageal cancer receivingradical dissectionof tumors and 3-field lymph nodes(including both sides of the neck, chest and abdomen) via the right chestincision. Methods The clinical data of166 patients with thoracic esophageal cancer, underwent subtotal esophageal excision and 3-field lymph node (including both sides of the neck, chest and abdomen) dissection via the right chest in our hospitalbetween Jan 2016 and Dec 2016,were retrospectively analyzed.According to with or without metastasis oftheir recurrent laryngeal nerve lymph nodes,all patients were divided into the study group (46 cases) and the control group (120 cases), and the possibleinfluencing factors for metastasis of recurrent laryngeal nerve lymph nodes, such asgender, tumor location, tumor size, pathologic types and so on, were identified by univariate analysis.Then multivariate Logistic regression analysis was conducted for those factors with statistical significance. Results The univariate analysis showed that there were significant differences in the age, metastasis ofsubcarinallymph node, differentiationdegree, invasion depth(T stage)between patients of thetwo groups(all P<0.05). Multivariate Logistic regression analysis showed thatdifferentiation degree and invasion depth were associated with the metastasis of recurrent laryngeal nerve lymph nodes(P<0.05). Conclusion The independent risk factors for metastasis of recurrent laryngeal nerve lymph nodesare differentiation degree and invasion depth of esophageal cancer. |
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