| Objective To explore the risk factors of abnormal ankle-brachial index (ABI) in those patients with type 2 diabetes mellitus (T2DM) and its correlation with osteoporosis.Methods From Apr 2016 to Dec 2016, 235 cases of T2DM patients hospitalized in our hospital were selected as the study objectives, and then divided into the lower ABI group (54 cases,ABI<0.9) and the normal ABI group (181 cases, 0.9 ≤ ABI < 1.3) according to their ABI values. The differences of such indexes as age, duration of diabetes, body mass index (BMI), fasting blood glucose (FBG), fasting C-peptide, glycosylated hemoglobin (HbA1c), triglyceride (TG), total cholesterol (TC), low-density lipoprotein (LDL), serum creatinine (SCr), estimated glomerular filtration rate(eGFR), uric acid(UA) andurine ratio of micro-albuminuria to creatinine (UACR) between the two groups were compared and analyzed. And logistic regression analysis was used to discuss the risk factors of ABI abnormality and the correlation between ABI and osteoporosis.Results Compared with the normal ABI group, the patients'age, duration of disease, levels of HbA1c, TG and UACR in the lower ABI group were much higher and their eGFR levels weremuch lower, with significant differences between the two groups (P<0.05). Logistic regression analysis showed that age, duration of disease, HbA1c, eGFR were risk factors of ABI abnormality(P<0.05). There was significant differencein the incidence of osteoporosis between the two groups(χ2=3.59, P<0.05). Correlation analysis showed that the T value of BMD was positively related with ABI (r=0.597, P<0.05).Conclusion Age, duration of diabetes, poor glucose control and low eGFR level are risk factors of ABI abnormality in those T2DM patients, and decrease of ABI value may beclosely associated with the incidence of osteoporosis. |
