Objective Analyze the pathogenic distribution of infections in chronic wounds and the clinical efficacy of topical vacuum sealing drainage (VSD) with continuous irrigation. Methods 58 cases of chronic wounds were selected from May 2015 to March 2017 in Anhui provincial hospital as the objects of study. A retrospective statistical analysis was performed on the results of the bacterial culture and drug sensitivity of the first wound secretions of hospitalization. Evaluate the infection control situation,times of treatment, wound cleaning time, wound area, complications and prognosis of the patients who underwent topical VSD with continuous irrigation treatment. Results 68 strains of pathogenic bacteria were cultured in 58 cases, of which 4 cases were negative, and the infection rate was 93.10%. There were 28 gram positive bacteria, accounting for 41.18%, and 40 gram negative bacteria, accounting for 58.82%. The main bacteria were distributed in Staphylococcus aureus (25%), Pseudomonas aeruginosa (20.59%), Escherichia coli (13.24%). 55 patients received topical VSD with continuous irrigation treatment. Infection symptoms were controlled;The number of patients receiving 1, 2, 3, and 4 treatments were 36, 13, 4, and 2, respectively; The cleaning time of wound was 6~43 days, average (14.40 + 8.93) days. After treatment, the average area of the wound was reduced (8.91 + 3.17) cm2; No obvious obstruction and serious complications occurred; After VSD removal,17 patients had primary healing, and 38 patients underwent two stage skin grafting or flap repair. Only one free flaps showed postoperative necrosis, and the rest of them survived. No cases developed further deterioration or recurrence infections of the wound; The excellent and good rate of treatment was 98.2%.Conclusion The main pathogens of infections in chronic wounds are Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli.Topical VSD with continuous irrigation treatment can effectively control infection, reduce wounds surface area and promote granulation tissue growth. |