| Objective To explore the changes of neutrophil/lymphocyte ratio (NLR) and its significance in acute intracerebral hemorrhage within 24 hours, and to evaluate the relationship between early functional deterioration and NLR. Methods A total of 157 cases of patients with intracerebral hemorrhage were recruited from the Department of Neurology in our hospital from January 2016 to August 2017. We analyzed white blood cells count (WBC), absolute neutrophil count (ANC), the absolute lymphocyte count (ALC), neutrophil/lymphocyte ratio (NLR) and other indicators for the evaluation of whether NLR was predictive for early neurological deterioration. Results There were 157 cases with acute cerebral hemorrhage, among whom 45 cases with deterioration were divided into ND group, and 112 cases without deterioration were categorized as non-ND group. White blood cell count(11.11±4.53)×109/L, neutrophil percentage (82.04±10.77)%, absolute neutrophil count (9.47±4.41)×109/L and the median of NLR in ND group were more higher than non-ND group, and the difference was statistically significant (P<0.05). The hematoma volume, NIHSS score (11.68±5.45) and the percentage of broking into ventricle in ND group significantly increased, and the difference was statistically significant (P<0.05). Compared to non-ND group, the lymphocyte percentage in ND group decreased, and the difference was statistically significant (P<0.05). By logistic regression analysis, admission neutrophil percentage, absolute neutrophil count, NHISS score and whether breaking into the ventricle were independent risk factors for early neurological deterioration in cerebral hemorrhage, and NLR was not an independent risk factor. Conclusion NLR may not be the risk factor related to early neurological deterioration in patients with acute cerebral hemorrhage. |
