Objective To observe the effect of postoperative multimodal analgesia on those patients with mixed hemorrhoids. Methods Ninety patients with grade I~Ⅱ mixed hemorrhoids, based on classification of the American Society of Anesthesiologists (ASA), underwent operations in our hospital between Jan 2016 and Nov 2017, were collected and divided into 3 groups by means of random number table,30 cases in each group. After operation, patients in group A were locally injected with single 0.596% ropivacaine mesylate for infiltration analgesia; group B were intravenously injected with sufentanil and granisetron for infusion analgesia; and group C were intramuscularly injected with nalbuphine hydrochloride on the basis of infusion analgesia in group B. The scores of pain visual analogue scale (VAS), adverse reactions, analgesia satisfaction and scores of sleep quality during the perioperative period in the three groups were recorded and compared. Results The VAS scores at each time points in group C were significantly lower than those in group A and B (all P<0.05). The incidence rates of such postoperative adverse reactions as dizziness, drowsiness, nausea and vomiting, urine retention and pruritus of skin were 13.33%, 0.00%, 13.33%, 20.00% and 0.00% in group A; 20.00%, 6.67%, 26.67%, 23.33% and 6.67% in group B; and 23.33%, 6.67%, 26.67%, 20.00% and 3.33% in group C, respectively, but no significant difference was found among the three groups (P>0.05). Patients in group C had significantly higher postoperative analgesia satisfaction (93.30%) and sleep quality score (4.36±1.47) than those in group A (36.67%; 7.58±1.95) and B (70.00%; 5.49±1.62) (P<0.05). Conclusion Application of multimodal analgesia after the mixed hemorrhoids surgery could evidently reduce the pain severity of patients, promote their sleep and improve their satisfaction, without the rising incidence of adverse reactions. |