| Objective To investigate the effect of high-flux hemodialysis (HFHD) on cardiac function in those patients with end-stage renal disease (ESRD). Methods A total of 62 patients with ESRD underwent maintenance hemodialysis (MHD) in our hospital between Jan 2015 and Dec 2016 were selected, and then divided into the HFHD group and the conventional hemodialysis group by means of random number table, 31 cases in each group. Changes of myocardial injury biomarkers (levels of cardiac troponin, B-type natriuretic peptide, serum creatinine, urea nitrogen, parathyroid hormone) and cardiac function parameters between the two groups were compared after treating for 6 months. Results The levels of parathyroid hormone, cardiac troponin T and B-type natriuretic peptide after dialysis in the HFHD group were significantly lower than those in the conventional dialysis group (P<0.05). The values of IVST, LVPWT and LVMI after dialysis in the HFHD group were much lower than those in the conventional dialysis group, but the LVEF value in the HFHD group was much higher than that in the conventional dialysis group, and the differences between them were statistically significant (all P<0.05). Conclusion Application of HFHD could effectively remove parathyroid hormones, and may have certain advantages over conventional hemodialysis in the improvement of cardiac function for those ESRD patients. |
