| Objective To investigate the predictive value of ultrasonography of fetal cervical translucency (NT) thickness, heart rate and axis in congenital heart disease (CHD) in early pregnancy. Methods The clinical data of 168 pregnant women gestationally aged 12 to 14 weeks who were admitted to this hospital from July 1, 2015 to July 1, 2017 were selected. All the pregnant women were single pregnancy. The fetal NT, heart rate and cardiac axis were measured by color Doppler ultrasound. All pregnant women were followed up for one week after delivery, and the number of cases of congenital heart disease in the first week after delivery was counted. The roc curves were plotted. The predictive value of NTR, heart rate and cardiac axis in fetal congenital heart disease was assessed. Results According to NT prediction in fetal congenital heart disease, the area under the ROC curve was 0.895 (P<0.001), the best point of fetal congenital heart disease was 2.995 mm, the sensitivity was 0.882, and the specificity was 0.961. According to arbor prediction in fetal congenital heart disease, the area under the ROC curve was 0.657 (P=0.021), the best point of fetal congenital heart disease was 50.891 degrees, the sensitivity was 0.643, and the specificity was 0.598. In heart rate prediction of fetal congenital heart disease, the area under the ROC curve was 0.616 (P=0.045), the best point of fetal congenital heart disease predicted by heart rate was 179 time/min, the sensitivity was 0.556, and the specificity was 0.879. Conclusion NT thickness, heart rate and cardiac axis ultrasound examinations in early pregnancy have certain clinical significance in predicting fetal congenital heart disease and cardiac malformation, and NT thickness has the most significant predicative value. |
