Objective To explore the possible influencing factors and mechanism of cerebral microhemorrhage. Methods Seventy-four cases of patients with acute cerebral infarction admitted to this hospital between Jan 2011 and Feb 2011 were selected and received regular sequence(T1WI, T2WI, FLAIR), DWI and T2-GRE scanning, then cerebral microbleed(CMB) was partitioned, counted and graded. According to the presence or absence of CMB, the patients were divided into CMB group(36 cases) and non-CMB group(38 cases). The age, smoking and drinking history, blood glucose, blood pressure, LDL and homocysteine levels were analyzed retrospectively. Results The proportion of patients with hypertension and lacunar cerebral infarction in CMB group was significantly higher than that in non-CMB group, showing a statistically significant difference(χ2=11. 013, P=0. 010; χ2=6.121, P=0. 012). Plasma biochemical examination results of the two groups showed no statistically significant difference(P > 0.05), inaddition to the UA、Cr. Logistic regression analysis showed that high blood pressure(OR=4.66, 95% CI:1.22~17.64, P=0.010), lacunar cerebral infarction(OR=4. 321, 95% CI:1.19~16.75, P=0.012) were risk factors for CMB. Conclusion CMB is closely related to hypertension and lacunar cerebral infarction, among which hypertension is the most important controllable risk factor of CMB. Lacunar cerebral infarction and the incidence of CMB may have similar mechanisms. |