| Objective To investigate the expression of ALK in 100 NSCLC patients, and further perform the contrastive analysis of its clinicopathological characteristics. Methods The clinical data of 100 cases of NSCLC patients hospitalized in the Second Hospital of Anhui Medical University fromJan. 2016 to Oct. 2017were collected,the expression of ALK was detectedby full-automatic immunohistochemistry, and the contrastive analysis between ALK and clinicopathological features was performedby SPSS statistical analysis. Results There were 6 cases of ALK positive patients in 100 cases, and the positive rate was 6%. The positive expression rate of ALK in patients with different age, tumor diameter and pathological type was significantly different (P<0.05). However, there was no marked difference in the positive expression rate of ALK among patients with different sex, smoking, location of occurrence and lymph node metastasis(P>0.05). Conclusion The expression of ALK inNSCLC patients is related to their age, lump size and pathological classification, which may provide important reference for the clinical diagnosis and treatment. |
