文章摘要
全身运动质量评估量表对早产脑损伤高危儿神经发育结局的预测价值
Value of GMs scale in prediction of neurodevelopmental outcome of high-risk children with premature brain injury
投稿时间:2018-09-12  
DOI:10.3969/j.issn.1000-0399.2019.03.003
中文关键词: 全身运动质量评估  早产脑损伤高危儿  神经发育结局  预测
英文关键词: General movement quality assessment  High-risk children with premature brain injury  Neurodevelopmental outcome  Prediction
基金项目:四川省卫生和计划生育委员会科研课题(项目编号:2016PJ170)
作者单位
张元铭 646000 四川省泸州市人民医院新生儿科 
杨盛泉 646000 四川省泸州市人民医院新生儿科 
艾莉莉 646000 四川省泸州市人民医院新生儿科 
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中文摘要:
      目的 探讨全身运动质量评估(GMs)量表评估早产脑损伤高危儿神经发育结局的临床价值。方法 选取2015年6月至2016年6月泸州市人民医院治疗的112例早产脑损伤高危儿,应用GMs量表分别对其扭动运动阶段和不安运动阶段全身运动质量进行评估,随访至12个月龄,以神经生物学结局(采用Gesell发育量表评估判定)为标准,评估对比GMs量表、52项神经运动检查的敏感性、特异性、阳性预测值和阴性预测值。结果 扭动运动阶段,GMs量表评估敏感性为72.73%、特异性81.11%、阳性预测值48.48%和阴性预测值92.40%;不安运动阶段,GMs量表评估敏感性为59.09%、特异性94.44%、阳性预测值72.22%和阴性预测值90.43%;52项神经运动检查敏感性为54.55%、特异性68.69%、阳性预测值30.00%和阴性预测值86.11%;不安运动阶段,GMs量表检测特异性、阳性预测值均大于52项神经运动检查结果,差异有统计学意义(P<0.05)。结论 GMs量表可准确预测早产脑损伤高危儿的神经发育结局,具有较高的特异性,值得在临床中推广使用。
英文摘要:
      Objective To evaluate the value of general movements scale (GMs scale) in the prediction of neurodevelopmental outcome in high-risk children with premature brain injury. Methods A total of 112 cases of high-risk children with premature brain injury admitted to our hospital from June 2015 to June 2016 were selected as the subjects. The GMs scale was used to evaluate the body motion quality of the writhing stage and the restless motor phase. The follow-up to 12 months of age was followed by 52 neuromotor examinations and the Gesell developmental scale was applied to examine the motor development outcomes (assessed using the Gesell Development Scale)of high risk infants with premature brain injury. Then the sensitivity, specificity, positive predictor, and negative predictor of the GMs scale and 52 neural motion tests were assessed, using neurological outcome as criteria. Results In writhing stage, the sensitivity by GMs scale was 72.73%, the specificity was 81.11%, the positive predictor was 48.48% and the negative predictor was 92.40%, while in restless motor stage, the sensitivity by GMs scale was 59.09%, the specificity was 94.44%, the positive predictor was 72.22% and negative predictor was 90.43%. The sensitivity, specificity, positive predictor, and negative predictor by 52 neural motion tests was 54.55%, 68.69%, 30.99%, and 86.11%, respectively. During restless motor stage, the specific and positive predictors of GMS scale were greater than those of 52 neurological exercises, and the difference was statistically significant (P<0.05). Conclusion GMs scale can be more accurate, effective and with high specificity in the prediction of high-risk children with premature brain injury, thus it is worth clinical promotion.
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