文章摘要
胸腔镜直视下经胸入路与超声引导下经皮入路胸椎旁神经阻滞对胸腔镜肺叶切除患者围术期镇痛的影响
Effects of ultrasound-guided paravertebral nerve block and thoracic approach to thoracic paravertebral blockade performed via video-assisted thoracoscope on postoperative analgesia in patients undergoing lobectomy
投稿时间:2019-07-01  
DOI:10.3969/j.issn.1000-0399.2020.09.001
中文关键词: 椎旁神经阻滞  胸腔镜手术  术后镇痛
英文关键词: Paravertebral block  Video-assisted thoracoscopic surgery  Postoperative analgesia
基金项目:安徽省重点研究与开发计划项目(项目编号:1804h08020286)
作者单位E-mail
汪姗 230001 合肥 中国科技大学附属第一医院(安徽省立医院)麻醉科  
章蔚 230001 合肥 中国科技大学附属第一医院(安徽省立医院)麻醉科  
柴小青 230001 合肥 中国科技大学附属第一医院(安徽省立医院)麻醉科 xiaoqingchai@163.com 
谢言虎 230001 合肥 中国科技大学附属第一医院(安徽省立医院)麻醉科  
王家武 230001 合肥 中国科技大学附属第一医院(安徽省立医院)麻醉科  
吴运香 230001 合肥 中国科技大学附属第一医院(安徽省立医院)麻醉科  
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中文摘要:
      目的 比较胸腔镜直视下经胸入路与超声引导下经皮入路胸椎旁神经阻滞(TPVB)对单孔胸腔镜肺叶切除患者术中麻醉管理及术后镇痛效果的影响。方法 选择2018年1月至2018年12月在中国科技大学附属第一医院(安徽省立医院)择期行单孔胸腔镜肺叶切除术的患者60例,ASA分级Ⅰ~Ⅲ级,采用随机数字法将其分为超声引导下经皮入路胸椎旁神经阻滞组(P组)和胸腔镜直视下经胸入路胸椎旁神经阻滞组(I组),每组30例。P组在术前由麻醉医师超声定位T4、T6椎旁间隙,I组在关胸前由外科医师在胸腔镜直视下定位T4、T6椎旁间隙,分别予以0.5%罗哌卡因10 mL,总量20 mL,行TPVB。两组患者均予以支气管内全麻,术后使用患者静脉自控镇痛(PCIA)。采用针刺法记录痛觉较对侧减退的节段数。记录两组患者TPVB的操作时间及阻滞皮区范围,记录入室后、插管后、手术5 min、手术30 min、术毕、拔管后的平均动脉压(MAP)、心率(HR),记录丙泊酚、瑞芬太尼的用量,两组患者拔管时间、恢复室的停留时间及烦躁、气胸、椎旁血肿(胸腔镜直视下判断)发生情况;分别记录手术后1、2、4、6、8、12、24、48小时两组患者静止和咳嗽时的VAS评分,术后PCIA泵的有效按压次数及舒芬太尼的消耗量。结果 操作时间I组低于P组,苏醒后痛觉阻滞范围I组大于P组,差异均有统计学意义(P<0.05);手术5 min、手术30 min两组患者的MAP、HR均有降低,且I组相较于P组降低更明显,差异均有统计学意义(P<0.05),I组术中丙泊酚、瑞芬太尼的用量,拔管时间、PACU停留时间均高于P组,差异有统计学意义(P<0.05),术后48 h内,两组患者各时间点静止、咳嗽时VAS评分、PCIA舒芬太尼的消耗量及患者满意度比较,差异无统计学意义(P>0.05)。P组有5例患者存在直径>5 mm的出血斑块,I组无直径>5 mm的出血斑块发生。结论 术前超声引导下TPVB可减少患者麻醉药用量,有利于患者术中麻醉管理,且苏醒较快,但可能出现胸壁出血、血肿;术中胸腔镜直视下TPVB,可避免反复穿刺及误注血管的风险,有利于患者术后镇痛;二者都有利于患者的预后,可根据情况适时选择实施。
英文摘要:
      Objective To compare the efficacy of ultrasound-guided thoracic paravertebral nerve block (TPVB) and thoracic approach to TPVB performed via the surgical field on intraoperative anesthesia management and postoperative analgesia in patients undergoing single-port video-assisted thoracoscope(VATS) lobectomy. Methods A total of 60 patients of both sexes, aged 39-65 yr, of American Society of Anesthesiologists Physical Status (ASA) I to Ⅲ, scheduled for VATS lobectomy, were divided randomly into two groups using a random number table method:ultrasound-guided TPVB group (group P) and thoracic TPVB group (group I),30 of each. In group P, patients underwent ultrasound-guided TPVB before surgery, while TPVB was performed before closing the chest by the surgeon in group I, and 0.375% ropivacaine 20mL was injected. Then general anesthesia and patient-controlled intravenous analgesia (PCIA) were performed in both groups. The time period to perform the blocks, the numbers of anesthetized dermatomes, hemodynamics,total remifentanil and propofol uesd during operation time, the postoperative pain scores and sulfentanil consumption were recorded. Visual analogue score (VAS) was recorded at 1, 2, 4, 6, 8, 12, 24, 48 hour after surgery. The occurrence of irritability, pneumothorax, paravertebral hematoma and patient satisfaction were also recorded. Results Compare with group I, the time period to perform the blocks of group P were longer (P<0.05). The numbers of anesthetized dermatomes in group P were less postoperatively (P<0.05) while the hemodynamics changed smoothly during surgery (P<0.05). The total dosage of remifentanil and propofol, extubation time, and time in PACU were more (P<0.05). In group P the occurrence of paravertebral hematoma was higher than that of group I (P<0.05). There existed no differences in VAS at rest or movement, sulfentanil consumption, nor the patients' satisfaction (P>0.05). Conclusions Both ultrasound-guided TPVB and thoracic approach to TPVB can enhance the efficacy of postoperative analgesia in patients undergoing lobectomy. Preoperative ultrasound-guided TPVB reduces the amount of anesthetics for patients, which is beneficial to the intraoperative anesthesia management of patients, and the recovery is faster, but it may cause chest wall bleeding. While thoracic approach to TPVB could avoid the risk of repeated puncture and accidental injection of blood. Anesthetists may weigh pros and cons before choosing the more appropriate solution.
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