| Objective To discuss the prognostic influence factors of acute kidney injury (AKI)patients with sepsis treated by continuous renal replacement (CRRT). Methods From January 2017 to May 2020, the clinical data of 70 AKI patients with sepsis in the department of Critical Care Medicine of the First Affiliated Hospital of USTC were analyzed retrospectively. According to the 28 days follow-up after CRRT treatment, the patients were divided into the survival group (22 cases) and the death group (48 cases). Age, gender, basic diseases, time and frequency of CRRT, mean arterial pressure (MAP), acute physiological and chronic health evaluation (APACHE) Ⅱ score, sequential organ failure (SOFA) score, white blood cell (WBC), platelet (PLT), neutrophil lymphocyte ratio (NLR), serum creatinine, urea nitrogen, c-reactive protein(CRP), procalcitonin (PCT), lactate (LAC), B-type natriuretic peptide precursor (pro-BNP), D-Dimer (D-D) were compared between the two groups. Logistic binary regression analysis was used to evaluate the influence factors which associated with the prognosis of the patients. Evaluate the predictive value of the prognosis of the patients by the operating characteristic curve (ROC) of patients. Results Single factor analysis showed that MAP, APACHE Ⅱ score and SOFA score were the influence factors of patients' 28 days mortality. Multivariate analysis showed that APACHE Ⅱ score and SOFA score were influence factors of the patients' prognosis. Conclusion CRRT is an important treatment of the AKI patients with sepsis. Our study showed that APACHE Ⅱ score and SOFA score are influence factors of the prognosis of the patients, which have an important reference value of evaluating prognosis. |
