文章摘要
ROI-C置入术和椎间融合器联合前路钛板术治疗多节段脊髓型颈椎病的疗效对比
Comparison of effects between ROI-C implantation and interbody fusion cage combined with anterior titanium plate fixation in treatment of multilevel cervical spondylotic myelopathy
投稿时间:2019-07-02  
DOI:10.3969/j.issn.1000-0399.2020.09.008
中文关键词: 颈椎桥型锁定融合器  颈前路减压植骨融合内固定术  脊髓型颈椎病
英文关键词: Cervical zero-profile anchored spacer  Anterior cervical decompression and bone grafting internal fixation  Cervical spondylotic myelopathy
基金项目:河南省教育厅科学技术研究重点项目(项目编号:19B320004)
作者单位
陈有 475001 开封 河南大学第一附属医院骨科一病区 
刘敏 475001 开封 河南大学第一附属医院骨科一病区 
杨广杰 475001 开封 河南大学第一附属医院骨科一病区 
王永胜 475001 开封 河南大学第一附属医院骨科一病区 
周炳康 475001 开封 河南大学第一附属医院骨科一病区 
马航 475001 开封 河南大学第一附属医院骨科一病区 
郭庆功 475001 开封 河南大学第一附属医院骨科一病区 
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中文摘要:
      目的 对比新型前路颈椎桥型锁定融合器(ROI-C)置入术和椎间融合器联合前路钛板术治疗多节段脊髓型颈椎病(MCSM)的临床疗效。方法 回顾性分析2014年7月至2019年1月河南大学第一附属医院骨科住院治疗的76例MCSM患者的临床资料,均行颈椎前路椎间盘切除减压、植骨融合内固定手术治疗,根据术中固定方式不同分为ROI-C组(35例,ROI-C置入固定)和对照组(41例,椎间融合器联合前路钛板固定)。记录两组患者手术时间、术中透视次数、失血量、术后并发症发生率等手术指标,术后1周、3个月、6个月以日本整形外科及骨科学会(JOA)评分、视觉模拟疼痛(VAS)评分评估手术效果。结果 与对照组相比,ROI-C组手术时间较短,术中透视次数和失血量较少,差异有统计学意义(P<0.05);两组患者术后住院时间及感染、血肿、神经损伤、食管损伤发生率比较,差异均无统计学意义(P>0.05),ROI-C组吞咽不适发生率2.86%低于对照组的19.51%,差异有统计学意义(P<0.05)。两组患者术后1周、3个月、6个月JOA评分随着时间改变依次升高,VAS评分依次降低,差异均有统计学意义(P<0.05);术后3个月、6个月颈椎生理曲度、椎间隙高度均较术前升高,差异有统计学意义(P>0.05);但两组患者术前、术后不同时间点JOA评分、VAS评分及颈椎生理曲度、椎间隙高度比较,差异均无统计学意义(P>0.05)。结论 ROI-C置入术、椎间融合器联合前路钛板术治疗MCSM均可取得满意疗效,有助于恢复颈椎生理弧度与椎间隙高度,但前者具有操作简便、手术时间短、术中透视次数和出血量少、术后吞咽不适发生率低等优点,可优先选择。
英文摘要:
      Objective To compare the clinical effect of new anterior cervical zero-profile anchored spacer (ROI-C) implantation and interbody fusion cage combined with anterior titanium plate fixation in the treatment of multilevel cervical spondylotic myelopathy (MCSM). Methods The clinical data of 76 patients with MCSM who were treated in Orthopedics Department, the First Affiliated Hospital of Henan University, between July 2014 and January 2019 were analyzed. All patients were treated with cervical anterior discectomy decompression and bone graft fusion internal fixation. According to different fixation methods in surgery, the patients were divided into ROI-C group (35 cases treated with fixation of ROI-C) and the control group (41 cases treated with fixation of interbody fusion cage and anterior titanium plate). The surgical parameters such as surgical time, frequency of intraoperative fluoroscopy, blood loss and complications were recorded. The surgical effects were evaluated by Japanese Orthopaedic Association (JOA) and visual analogue scale (VAS) scores 1 week, 3 months, 6 months after surgery. Results Compared with control group, the surgical time was significantly shorter, the frequency of intraoperative fluoroscopy and blood loss were significantly less in ROI-C group (P<0.05). There was no significant difference in postoperative hospital stay, incidence of infection, hematoma, nerve injury or esophageal injury between the two groups (P>0.05). The incidence of swallowing discomfort in ROI-C group was only 2.86%, significantly lower than that in control group (19.51%) (P<0.05). 1 week, 3 months and 6 months after surgery, JOA scores of the two groups significantly increased in turn, while VAS scores significantly decreased in turn (P<0.05). 3 months and 6 months after surgery and in the last follow-up, cervical physiological curvature and height of intervertebral space were significantly higher than those before surgery (P>0.05). However, there was no significant difference in JOA scores, VAS scores, cervical physiological curvature or height of intervertebral space between ROI-C group and control group before and after surgery (P>0.05). Conclusions The curative effects of both ROI-C implantation and interbody fusion cage combined with anterior titanium plate surgery are satisfactory in the treatment of MCSM. They are conductive to the recovery pf cervical physiological curvature and height of intervertebral space. However, the former is with advantages such as simple operation, short duration, little intraoperative fluoroscopy and blood loss, and low incidence of postoperative swallowing discomfort. So, it can be the priority.
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