文章摘要
CURB-65qSOFA评分对社区获得性肺炎患者的预后预测价值
Value of qSOFA and CURB-65 scores for prognosis prediction in patients with emergency community-acquired pneumonia
投稿时间:2020-09-17  
DOI:10.3969/j.issn.1000-0399.2021.02.006
中文关键词: 急诊社区获得性肺炎  预后  qSOFA评分  CURB-65评分
英文关键词: Emergency community-acquired pneumonia  Prognosis  QSOFA score  CURB-65 score
基金项目:安徽省临床医学应用项目(项目编号:08B063)
作者单位E-mail
梁培培 230022 合肥 安徽医科大学第一附属医院急诊ICU  
俞风 230022 合肥 安徽医科大学第一附属医院急诊ICU yufeng1110@sina.com 
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中文摘要:
      目的 探讨qSOFA、CURB-65评分对社区获得性肺炎(CAP)患者的预后预测价值。方法 选择2016年6月至2019年10月安徽医科大学第一附属医院急诊门诊收住院的312例社区CAP患者。根据住院治疗结局,分为非死亡(n=262)与死亡组(n=50);根据2016年版中国成人CAP诊断与治疗指南中CAP诊断及分级标准,分为重症CAP组(n=109)与非重症CAP组(n=203)。以重症CAP和死亡作为不良预后指标,采用受试者工作特征曲线分析qSOFA、CURB-65评分对不良预后的预测效能,并对qSOFA评分量表进行改良,优化预测效能。结果 qSOFA评分、CURB-65评分和Age-Lac-qSOFA评分预测死亡的曲线下面积(AUC)分别为0.856、0.860和0.956,特异度分别为92.00%、97.04%和91.52%,灵敏度分别为49.80%、38.14%和83.45%。预测重症CAP的AUC分别为0.835、0.846和0.958,特异度分别为89.80%、83.24%和97.15%,灵敏度分别为58.14%、70.30%和79.89%。结论 CURB-65评分与qSOFA评分对急诊重症CAP及死亡预后预测价值相仿。优化调整后Age-Lac-qSOFA评分,提高了对重症CAP及死亡预后的预测效能,且具有更高的灵敏度。
英文摘要:
      Objective To investigate the clinical values of qSOFA and CURB-65 scores in predicting the prognosis of community-acquired pneumonia patients in the emergency department. Methods A total of 312 community-acquired pneumonia patients were selected from the Emergency Department of our hospital from June 2016 to October 2019.According to the outcome of hospitalization,they were divided into thenon-death group(262 cases) and the death group(50 cases);the severe community acquired pneumonia group(109 cases) and the non-severe community acquired pneumonia group(203 cases),according to the severity of pneumonia. Using severe CAP and death as poor prognostic indicators, the predictive efficacy of qSOFA and CURB-65 scores was analyzed by receiver operating characteristic curve, and the predictive performance of qSOFA scoring scale was improved and optimized. Results The predicted AUC values of qSOFA score, CURB-65 score and Age-Lac-qSOFA score was 0.856, 0.860 and 0.956, respectively, their specificity was 92.00%,97.04% and 91.52%,respectively, and the sensitivity was 49.80%, 38.14% and 83.45%, respectively. The predicted AUC value of severe CAP was 0.835,0.846 and 0.958, respectively,the specificity was 89.80%,83.24% and 97.15%, respectively, and the sensitivity was 58.14%,70.30% and 79.89%, respectively. Conclusions There is no statistical difference in comparing CURB-65 score and qSOFA score in emergency severe CAP and death prognosis prediction.The optimized Age-Lac-qSOFA score improves the prediction efficiency of severe CAP and death prognosis with higher sensitivity.
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