| Objective To analyze the value of endoscopic ultrasonography guided fine-needle aspiration (EUS-FNA) in the diagnosis of pancreatic tumors. Methods Forty-four patients with suspected pancreatic space-occupying lesions who underwent EUS-FNA in the First Affiliated Hospital of Henan University from January 2017 to January 2019 were screened. With surgical pathological findings as the golden standard, the value of EUS-FNA in the differential diagnosis of benign and malignant pancreatic tumors was evaluated, and its diagnostic efficiency was evaluated. Results ①EUS-FNA detected malignant lesions in 27 cases and benign lesions in 17 cases. The diagnostic sensitivity, specificity, accuracy, positive predictive value and negative predictive value was 92.00%, 78.94%, 86.36%, 85.19% and 88.23%, respectively. The kappa value was 0.718. ②The largest diameter of benign pancreatic masses was shorter than that of malignant pancreatic masses. The proportions of lesions with cystic structures and clear boundaries were higher than those in patients with malignant lesions (P<0.05). ③EUS-FNA confirmed 28 cases (93.33%) of solid pancreatic tumors, 8 cases (72.73%) of pancreatic cysts and 2 other cases (66.67%). The diagnostic sensitivity, specificity and accuracy of EUS-FNA for solid pancreatic tumors was 95.83%, 83.33% and 93.33%, respectively. The diagnostic sensitivity, specificity and accuracy for pancreatic cysts was 75.00%, 71.43% and 72.73%, respectively. The diagnostic sensitivity, specificity and accuracy for other lesions was 50.00%, 100.00% and 66.67%, respectively. Conclusions EUS-FNA is highly consistent with surgical pathology in the diagnosis of benign and malignant pancreatic tumors, especially for solid tumors. The diagnostic value for cystic tumors is relatively lower. Tissue extraction has a significant impact on the diagnostic accuracy of EUS-FNA. |
