| Objective To study the curative effect of frozen therapy of bronchobronchial tuberculosis under fiberoptic bronchoscope on granulomatous proliferative bronchial tuberculosis and its safety. Methods Sixty patients with granulation proliferative bronchial tuberculosis admitted to Yangzhou Third People’s Hospital (June 2015 ~ May 2019) were divided into two groups according to the treatment plan. The control group was given routine anti-tuberculosis treatment, and the observation group was given frozen treatment under fiberoptic bronchoscopy on the basis of the control group. The efficacy of the two groups after four weeks of treatment, the time of conversion of sputum bacteria to yin, forced expiratory volume (FEV1), procalcitonin (PCT), erythrocyte sedimentation rate (ESR), hypersensitive C reactive protein (CRP) levels before treatment and the adverse reactions (such as chest pain, bleeding, dyspnea) during treatment were observed. Results The total effective rate in the observation group was higher than that in the control group (P<0.05), the time of sputum conversion shorter than that in the control group (P<0.05), the incidence of adverse reactions higher than that in the control group, and the difference was not statistically significant (P>0.05). FEV1 of the two groups increased after treatment, PCT, CRP, ESR decreased compared with those before treatment, and the difference of the above indexes in the observation group was more obvious than that in the control group (P<0.05). Conclusions The frozen treatment of granulation proliferative bronchial tuberculosis under fiberoptic bronchoscopy has remarkable curative effect, which can inhibit the release of inflammatory factors, shorten the time of phlegm bacteria turning negative, and has good safety. |
