Objective To compare the clinical efficacy of laparoscopic pyloromyotomy and open surgery in the treatment of hypertrophic pyloric stenosis (HPS).Methods The clinical data of 65 patients with hypertrophic pyloric stenosis in the Department of Pediatrics, the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital) from July 2015 to December 2019 were retrospectively analyzed. The clinical data were statistically described and analyzed. According to the operation method, the patients were divided into laparoscopic group (n=37) and open surgery group (n=28).According to whether the children were treated with infusion before operation, they were divided into the infusion group (n=14) and the non-infusion group (n=50), and the differences in the laboratory resources of the two groups were analyzed and compared. The operation effect and prognosis of the two groups were evaluated, and the differences inintraoperative bleeding, operation time, total hospitalization time, postoperative hospital stay and complications between the two groups were compared. According to whether the children were treated with infusion before operation, they were divided into infusion group (n=14) and non-infusion group (n=50), and the differences in laboratory parameters between the two groups were analyzed and compared. Results All cases were successful; there were no recurrence cases, two cases of laparoscopic conversion to open (1 case due to mucosal damage, and 1 case had insufficient operation space due to abdominal distension).The total hospitalization time of laparoscopic group was (9.73±3.24) days and postoperative hospital stay was (5.81±1.97) days, which were lower than those of open group(P<0.05). The serum Na (137.54±2.67) mmol/L, Cl (98.76±5.39) mmol/L and osmotic pressure (271.67±5.33) mmol/L in infusion group were significantly higher than those in non-infusion group (P<0.05).Conclusions The two surgical methods are safe and effective for the treatment of HPS. Laparoscopic pyloromyotomy can reduce the total length of hospital stay and achieve quicker recovery after operation. Early fluid resuscitation for patients with HPS is helpful to correct electrolyte disorder. |