| Objective To explore the levels of blood glucose and pregnancy outcomes in patients with gestational diabetes mellitus (GDM), and to analyze their related risk factors. Methods From January 2018 to June 2019, a total of 105 patients with GDM were selected in the Department of Obstetrics, the Chaohu Hospital of Anhui Medical University. All of the subjects were divided into good group(55 cases) and non-good group (50 cases) according to whether the fasting blood glucose level was up to standard during prenatal period, and their relevant indicators and risk factors were explored. Results The levels of FBG and 2 h PBG before and after delivery were significantly different between the two groups (P<0.05), but the D-value showed no significant difference between the two groups(P>0.05). The blood glucose level of patients in good group was lower than that in non-good group(P<0.05).Likewise, pregnancy-induced hypertension, oligohydramnios, premature rupture of membranes, premature delivery and macrosomia, the incidence of adverse pregnancy outcome sassociated with metabolic factors were lower in good group than those in non-good group (P<0.05). Multiple logistic regression analysis indicated that the age equal or greater than 35 years old was a risk factor for controlling blood glucose level, and the same with their pre-pregnancy BMI equal or greater than 24 kg/m2 (P<0.05). On the contrary, senior high school education or above was a protective factor(P<0.05). Receiver operator characteristic curve analysis showed the optimal truncation value of pre-pregnancy BMI was 21.935 kg/m2for predicting the risk of controlling blood glucose level, and the area under the curve was 0.725, the sensitivity was 80.00%, and the specificity was 60.00%. Conclusions The abnormal glucose metabolism in patients with GDM is consistent during pregnancy with postpartum. The level of blood glucose controlled effectively could reduce the adverse pregnancy outcomes associated with metabolic factors. The patients with GDM accompanied by older pregnancy or pre-pregnancy overweight or poor education are the main population for clinical intervention. |
