| Objective To find out the prognostic factors affecting the prognosis of cardiogenic shock patients treated with ECMO. Methods Twenty-five patients treated with ECMO from January 2017 to September 2020 in the First Affiliated Hospital of USTC (Anhui Provincial Hospital) were retrospectively studied. According to the wearing, the patients were divided into to successful group(n=18) and failed group(n=7).They also were divided into survival group(n=11) and non-survival group(n=14).According to 28-day survival after hospital discharge, Tn, CK-MB, Bil and creatinine were recorded, and the difference in these indicators was compared in different groups. The multivariate logistic regression analysis on the statistically significant indicators of single factor analysis was carried out. These indicators for predicting prognosis were assessed using the receiver operating characteristic (ROC) curve. Results Tn and CK-MB within 24h and CK-MB with 48h differences were lower in successful weaning group than those in failure group, and the differences were statistically significant. Bil within 24 h and 48h difference was higher in survival group than that in non-survival group, and the difference was statistically significant. Multivariate logistic analysis showed that Tn within 24 h difference was a protective factor for weaning group(P=0.036); Bil within 24 h difference (P=0.041) and length of stay(P=0.045) were protective factors for 28-day survival. ROC curve analysis showed that the area under ROC curve (AUC) of the length of stay, Tn and Bil within 24 h difference was 0.893, 0.825 and 0.786, respectively, and the optimal cur-off value was 20.41,3.65 and 14.50, respectively. Conclusions Tn, Bil within 24 h difference and length of hospital stay have good predictive value for the prognosis of patients with ECMO, which should be observed dynamically. |
