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| 子痫前期孕妇分娩小于胎龄儿的危险因素及其与孕检次数的关系 |
| Study on relationship between number of preeclampsia pregnant women's birth check-ups and risk of childbirth small for gestational age |
| 投稿时间：2021-10-13 |
| DOI：10.3969/j.issn.1000-0399.2022.03.012 |
| 中文关键词: 子痫前期 孕妇 孕检次数 危险因素 小于胎龄儿 |
| 英文关键词: Preeclampsia Pregnant women Number of birth checkups Risk factors Small-for-gestational-age infants |
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| 摘要点击次数: 926 |
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| 中文摘要: |
| 目的 探讨子痫前期孕妇分娩小于胎龄儿的危险因素及其与孕检次数的关系。方法 回顾性分析2018年4月至2020年10月江南大学附属医院收治的106例子痫前期孕妇的临床资料,依据孕妇是否分娩小于胎龄儿分为分娩小于胎龄儿组(35例)及非分娩小于胎龄儿组(71例)。比较两组孕妇的一般资料、孕期用药、合并症及孕期孕检次数等指标,将差异有统计学意义的指标纳入logistic回归分析子痫前期孕妇分娩小于胎龄儿的危险因素。根据孕妇分娩前总孕检次数不同分为孕检≤3次组(28例),孕检4~6次组(35例)和及孕检≥7次组(43例)。比较上述3组孕妇分娩小于胎龄儿的发生率,采用Spearman分析孕妇孕检次数与孕妇分娩小于胎龄儿发生率的关系。结果 与非分娩小于胎龄儿组孕妇比较,分娩小于胎龄儿组孕妇吸烟或被动吸烟、未服用叶酸、产前最高收缩压>180 mmHg、孕检次数≤3次构成比更高,差异均有统计学意义(P<0.05);logistic多因素回归分析显示,吸烟或被动吸烟、未服用叶酸、孕检次数≤3次是影响子痫前期孕妇分娩小于胎龄儿发生的独立危险因素(OR=3.951、3.274、4.923,P均<0.05);孕检≤3次组孕妇分娩小于胎龄儿发生率高于孕检4~6次组及孕检≥7次组,且孕检4~6次组孕妇分娩小于胎龄儿发生率高于孕检≥7次组,差异均有统计学意义(P<0.05);Spearman分析显示,孕妇孕检次数与孕妇分娩小于胎龄儿发生率呈负相关(r=-0.547,P<0.05)。结论 吸烟或被动吸烟、未服用叶酸、孕检次数是子痫前期孕妇分娩小于胎龄儿的危险因素,孕检次数与孕妇分娩小于胎龄儿发生率呈负相关。 |
| 英文摘要: |
| Objective To explore the risk factors of preeclampsia pregnant women delivering small-for-gestational-age infants and their relationship with the number of pregnancy tests.Methods The data of 106 pregnant women with preeclampsia admitted to the Affiliated Hospital of Jiangnan University from April 2018 to October 2020 were retrospectively analyzed.According to whether pregnant women gave birth to small-for-gestational-age infants or not, they were divided into a small-for-gestational-age infant group (35 cases) and a non-delivery small-for-gestational-age infant group (71 cases).The general information, medication during pregnancy, comorbidities and the number of pregnancy examinations during pregnancy were compared between the two groups, and the indicators with statistically significant differences were included in the Logistic regression analysis to analyze the risk factors for the occurrence of small-for-gestational-age infants in pregnant women with preeclampsia.According to the total number of pregnancy examinations before delivery, the pregnant women were divided into 28 cases in the group of ≤3 times of pregnancy inspection, 35 cases in the group of 4 to 6 times of pregnancy inspection, and 43 cases in the group of ≥7 times of pregnancy inspection.The incidence of small-for-gestational-age infants delivered by pregnant women in the above three groups was compared, and the relationship between the number of pregnancy examinations and the incidence of small-for-gestational-age infants was analyzed by Spearman.Results Compared with pregnant women in non-delivery small-for-gestational-age group, pregnant women in delivery small-for-gestational-age group had higher proportions of smoking or passive smoking, not taking folic acid, highest prenatal systolic blood pressure >180mmHg, and frequency of pregnancy examinations ≤3,andthe difference were statistically significant (P<0.05). Logistic multivariate regression analysis showed that smoking or passive smoking, not taking folic acid, and the number of pregnancy examinations ≤3 were independent risk factors for the occurrence of small-for-gestational-age infants in pregnant women with preeclampsia (OR=3.951, 3.274, 4.923, P<0.05,P<0.05).The incidence of small-for-gestational-age infants in pregnant women with "≤3 times" pregnancy examinations was higher than that in "4~6 times"and "≥7 times" pregnant women (P<0.05), and the incidence of small-for-gestational-age infants in pregnant women with "4-6 times" pregnancy test was higher than that in pregnant women with "≥7 times" pregnancy test (P<0.05).Spearman analysis showed that the number of pregnancy examinations was negatively correlated with the incidence of small-for-gestational-age infants (r=-0.547, P<0.05).Conclusions The risk factors of preeclampsia pregnant women giving birth to small-for-gestational-age infants include smoking or passive smoking, not taking folic acid, and the number of pregnancy tests. The number of pregnancy examinations is negatively correlated with the incidence of small-for-gestational-age infants delivered by pregnant women. |
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