| Objective To evaluate the effect of silicone oil filling on peripapillary vessel density (VD) and retinal nerve fiber layer (RNFL) thickness in patients with rhegmatogenous retinal detachment (RRD) by using optical coherence tomography angiography (OCTA). Methods A total of 18 RRD patients who underwent vitrectomy combined with silicone oil filling in the First Affiliated Hospital of Anhui Medical University from January 2019 to August 2022 were randomly selected as the case group, and another eye was selected as the control group (15 cases). Results There were 10 males and 8 females in the enrolled 18 patients; their age ranged from 32 to 65 years, with an average of (50.89±9.90) years old. The time of silicone filling range from 91 to 223 days， with an aver time of (149.27±36.51) days. The peripapillary VD in the case group (45.21±5.57) was lower than that in the control group [ (45.21±5.57) vs (52.50±3.34), %], and the difference was statistically significant (P＜0.05). The VD of the eight peripapillary regions including nasal superior, nasal inferior, inferior nasal, inferior tempo, tempo inferior, tempo superior, superior tempo, and superior nasal in the case group was also lower than that in the control group (P all <0.05, respectively). There were no significant differences in the peripapillary RNFL and eight peripapillary areas between the two groups (P all > 0.05). Then, no correlation was found among VD, RNFL and SO filling time (P all >0.05). Conclusions Peripapillary VD may decrease in SO filling eyes of RRD patients, but there is no significant change in peripapillary RNFL. |
