| Objective To explore the relationship between outdoor air pollutants and low birth weight. Methods From January 2018 to December 2019, the clinical date of 261 cases of low birth weight infants and 5 872 cases of healthy term infants were analyzed retrospectively. To analyze the differences between low birth weight infants and full-term infants were analyzed in terms of gestational age, maternal age, cesarean section, current delivery situation, pregnancy complications, pregnancy hypertension syndrome, pregnancy medication history and other confounding factors. The data of air pollutants were from eight air quality monitoring stations in the city, and the individual exposure levels of PM10, PM2.5, SO2, NO2, CO and O3 of pregnant women during the early pregnancy (T1) and middle pregnancy (T2) were calculated. Logistic regression model was used to analyze the relationship between air pollution exposure and low birth weight of newborns. Results A total of 261 low birth weight newborns (4.3%) were found among 6 133 single birth live births. Comparing low birth weight and normal full-term infants, it was found that the CO exposure dose of pregnant women during the early pregnancy (T1) was significantly different (P＜0.05). The results of logistic analysis showed that gestational age, cesarean section were all risk factors for low birth weight (OR=43.448、 2.131),but no statistical significance was found between air pollutants and low birth weight of newborn. Conclusion Although this study finds that the exposure dose of CO might affect the birth weight, it does not find that the air pollutants in different pregnancy periods were independent risk factors for low birth weight of newborns. |
