| Objective To explore the current situation and influencing factors of multiple drug use in elderly retired cadres. Methods Retrospective collection and analysis were carried out on 226 elderly military cadres supported by the 986 Air Force Hospital from December 2019 to December 2021. They were divided into non multi drug group(2~4 drugs), multi drug group (5 drugs or more) according to the number of drugs they used. The clinical data of the subjects were collected, the influencing factors of multiple medication among retired cadres were analyzedwith logistic regression model, a database was established with Excel software, and the top ten commonly used drug categorieswere screened out. Lexicomp Drug Interactions database was used to analyze and evaluate drug drug interactions (DDIs). Results Logistic regression model analysis results showed that educational level (OR=1.783，P=0.012), chronic comorbidity (OR=7.546, P<0.001), medication compliance (OR=6.430, P<0.001), adverse drug reactions (OR=1.904, P =0.003) were the influencing factors of multiple medication among retired cadres. The most frequent occurrence of DDIs was antihypertensive drugs, cardiovascular system drugs, anticoagulant drugs and antiosteoporosis drugs in sequence. Conclusions The proportion of multiple medication among elderly retired cadres is relatively high. Among them, education level, chronic disease comorbidity, medication compliance, and adverse drug reactions are the influencing factors of multiple drug use among retired cadres, so they should be guidedtoconductindividualized drug usein clinics. |
