Objective To compare the clinical effectiveness of three distinct surgical approaches for managing early glottic laryngeal carcinoma extending into the anterior commissure so as to serve as a valuable reference for clinicians when choosing the most appropriate treatment method in clinical practice. Methods From March 2014 to March 2022, 76 patients with early glottic laryngeal carcinoma involving the anterior commissure in the Department of Otorhinolaryngology, Head and Neck Surgery were retrospectively analyzed in Lu'an People's Hospital. These patients were categorized into the plasma group (treated with lowtemperature plasma laryngeal partial resection under supporting laryngoscopic microscope, 27 cases), the open group (treated with open laryngeal partial resection, 27 cases) and the CO2 laser group (treated with CO 2 laser partial laryngectomy under supporting laryngoscope microscope, 22 cases) according to different surgical treatments. A comparison was made among the three groups regarding operation-related indicators, postoperative complications, and recurrence rate. Results The three groups exhibited significant variances in terms of operation time, intraoperative blood loss, duration of postoperative hospital stay, and mucosal recovery score (P<0.05). There were significant differences between the plasma group and the open group (P<0.05), and between the CO2 laser group and the open group (P<0.05). There were no significant differences in the operation time, intraoperative blood loss, postoperative hospital stay and mucosal recovery score between the plasma group and the CO2 laser group (P=0.581, P=0.482, P=0.647, P=0.198).The occurrence of postoperative complications showedno significant variation among the three groups (P=0.384). However, the open group and the plasma group exhibited a lower postoperative recurrence rate than the CO2 laser group, with statistically significant differences (P=0.004, P=0.016). Conclusions For patients with early glottic laryngeal carcinoma involving the anterior commissure, low-temperature plasma laryngectomy under the retaining laryngoscope and microscope offers the benefits of minimal operation time, reduced trauma, accelerated postoperative recovery, and a low incidence of recurrence. It is a surgical method worthy of choice in clinical treatment. |