Objective To explore the influencing factors of anxiety and depression in patients with chronic constipation (CC). Methods From April 2021 to July 2023, data were collected from 150 patients diagnosed with CC in the Department of Gastroenterology at the Affiliated Hospital of Anhui Medical University. Patients were divided into the anxiety group and non-anxiety group, the depression group and non-depression group based on anxiety and depression scores. General information (gender, age, BMI, duration of constipation, presence of abdominal pain, constipation treatment, education level), PAC-SYM score, PAC-QOL score,GCQ score, and EAT-26 score were compared between the two groups. Univariate and multivariate logistic regression analyses were used to determine the risk factors for anxiety and depression in CC patients. Results Among CC patients, 48 (32.0%) had anxiety, 41 (27.3%) had depression, and 46 (30.7%) were in the high-risk group for eating disorders. CC patients with anxiety and depression had significantly higher PAC-SYM and PAC-QOL scores compared to those without anxiety and depression, while the GCQ score was significantly lower in the anxiety and depression groups. The proportion of patients in the high-risk group for eating disorders was significantly higher than that in the non-anxiety and depression groups, with statistically significant differences. Disease duration ≥3 years and presence of abdominal pain were independent risk factors for anxiety and depression in CC patients, while receiving constipation treatment was a protective factor for anxiety. Conclusion Anxiety and depression in CC patients worsen constipation symptoms and reduce quality of life and comfort. Disease duration ≥3 years and presence of abdominal pain are independent risk factors for anxiety and depression, while receiving constipation treatment is a protective factor for anxiety. |