| Objective To compare the nutritional indexes and glycolipid metabolism indexes of elderly chronic heart failure (CHF) patients with different tranditional Chinese medicine(TCM) syndromes. Methods The clinical data of 126 elderly patients with CHF who treated in Huaxian Hospital of TCM from June 2021 to October 2023 were analyzed retrospectively. According to TCM dialectical analysis, they were divided into the deficiency of both Qi and Yin group (n=42), Qi deficiency of heart and lung group (n=28), Qi deficiency and and blood-stasis group (n=33) and Yang deficiency of heart and kidney group (n=23). The differences in clinical data (age, sex, body mass index, blood pressure), cardiac function indexes [(cardiac function grade, 6-minute walking test (6MWT) distance, left ventricular ejection fraction (LVEF), left ventricular end-systolic diameter (LVESD) and left ventricular end-diastolic diameter (LVEDD)], glycemic and lipid metabolism indexes (fasting blood glucose, HbA1c, total cholesterol (TC), triacylglycerol (TG), high density lipoprotein (HDL-C) and low density lipoprotein (LDL-C)) and nutritional indexes [albumin (Alb) and geriatric nutritional risk index(GNRI))] among the four groups were compared. Results The LVEF of Yang deficiency of heart and kidney group was lower than that of deficiency of both Qi and Yin group and Qi deficiency of heart and lung group ( all P<0.05). The Alb in deficiency of both Qi and Yin syndrome group was lower than that in Qi deficiency of heart and lung group, Qi defieiency and and blood-stasis group and Yang deficiency of heart and kidney group(all P<0.05), The GNRI was lower than that of Qi deficiency of heart and lung group and Yang deficiency of heart and kidney, and the proportion of patients with malnutrition risk was significantly higher than that of Qi deficiency of heart and lung group, Qi deficiency and blood stasis and Yang deficiency of heart and kidney group (all P< 0.05); the TC and LDL-C in Qi-deficiency and blood-stasis group were higher than those in the deficiency of both Qi and Yin group, Qideficiency of heart and lung group and Yang deficiency of heart and kidney group(P<0.05), and the TG was higher than that of the Yang deficiency of heart and kidney group (P<0.05). Conclusions The nutritional risk and glucose and lipid metabolism characteristics of CHF patients with different TCM syndrome types are different. Among them, the nutritional risk of patients with deficiency of both Qi and Yin syndrome is higher, the blood lipid level of patients with Qi deficiency and blood-stasis syndrome is relatively higher, and the heart function of patients with Yang deficiency of heart and kidney syndrome is relatively poor. Therefore, TCM clinical dialectical treatment can be specific to different syndrome types. |
