| Objective To observe the clinical effect of concentrated growth factor application in the extraction of mandibular low impacted third molars while compared with collagen plug. Methods From Feburary 2023 to March 2024, 48 patients with bilateral mandibular impacted third molars in the Outpatient Department of Oral and Maxillofacial Surgery, Hefei Stomatological Hospital were selected.These patients were chosen based on obvious clinical symptoms or as part of an orthodontic treatment plan. A self-controlled clinical trial design was applied in this study.The patient had the bilateral impacted third molar extracted successively. In order to promote wound healing, the extraction sockets were filled with CGF gel and collagen plugs, respectively. The postoperative bleeding at 30 minutes and 24 hours, pain, swelling, limitation of mouth opening and dry socket on the 1st, 3rd and 7th day after operation were observed. Results There was no significant difference in surgical time, bleeding, and dry socket syndrome between the CGF and collagen plug groups (P>0.05). However, there were significant time effects and inter-group effects observed in postoperative mouth opening, VAS pain score, and swelling degree between the two groups (P < 0.05). Further analysis revealed that on the first and third day after surgery, the CGF group had a higher degree of mouth opening than the collagen group while also experiencing lower VAS pain scores and less swelling; these differences were statistically significant (P < 0.05). There was no significant difference in the degree of mouth opening, VAS pain score and swelling between the CGF group and the collagen group on the 7th day after operation (P>0.05). Conclusions Compared with collagen plug filling, CGF gel is more effective in improving early postoperative pain, facial swelling, and mouth opening in patients with impacted mandibular third molar extraction. |
