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弥散加权成像联合甲胎蛋白对原发性肝癌早期诊断价值 |
ValueofDWIcombinedwithAFPinearlydiagnosisofprimaryhepaticcance |
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DOI: |
中文关键词: 原发性肝癌 弥散加权成像 磁共振成像 |
英文关键词: Primaryhepaticcancer Diffusionweightedimaging Magneticresonanceimagin |
基金项目: |
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中文摘要: |
目的 探讨弥散加权成像(DWI)联合甲胎蛋白(AFP)对原发性肝癌(PHC)早期诊断价值。方法 回顾分析34例
经手术或穿刺活检病理证实为肝癌患者的临床资料,患者均行放射免疫法检测血清AFP并行MRI常规扫描及DWI序列扫描。
结果 AFP、DWI联合AFP诊断PHC的敏感度、特异度、阳性预测值、假阳性率、阴性预测值及假阴性率分别是:AFP(200ng/L)为
3750%,10000%,10000%,000%,909% 和6250%;AFP(400ng/L)为3125%,10000%,10000%,000%,833% 和
6875%;DWI联合AFP(200ng/L)为7813%,5000%,9615%,2000%,1250% 和2188%;DWI联合AFP(400ng/L)为
7186%,5000%,9615%,2000%,1000%和2813%。结论 DWI联合甲胎蛋白可以提高PHC诊断率,为PHC的早期诊断提
供了有效依据。 |
英文摘要: |
Objective TostudythevalueofDWIcombinedwithAFPintheearlydiagnosisofprimaryhepaticcancer
Methods Theclinicaldataof34casesofpostoperativemetastasisorrecurrenceofprimaryhepaticcancerconfirmedbysurgeryorpuncture
biopsywereretrospectivelyanalyzedAllthepatientsunderwenttheradioimmunoassaydetectionofserumalphafetoprotein(AFP)leveland
DWIResults Inthe34cases,thesensitivity,specificity,positivepredictivevalueandnegativepredictivevalueforAFP(200ng/L)was
3750%,10000%,10000%,000%,909%,and6250%,respectively;forAFP(400ng/L)was3125%,10000%,10000%,
000%,833%,and6875%,respectively;forDWI+AFP(200ng/L)was7813%,5000%,9615%,2000%,1250%,and2188%,
respectively;forDWI+AFP(400ng/L)was7186%,5000%,9615%,2000%,1000%,and2813%,respectivelyConclusion DWI
combinedwithAFPissensitivetoprimaryhepaticcancer,anditprovideseffectivebasisfortheearlydiagnosisofprimaryhepaticcance |
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