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| 宫颈上皮内瘤变Ⅲ级行宫颈锥切术105例分析 |
| Clinical analysis of 105 patients with CIN Ⅲ treated by cold knife cervical conization |
| 投稿时间：2015-01-26 修订日期：2015-03-05 |
| DOI：10.3969/j.issn.1000-0399.2015.05.003 |
| 中文关键词: 宫颈上皮内瘤变 鳞状细胞相关抗原 人类乳头状病毒 |
| 英文关键词: Cervical intraepithelial neoplasia Squamous cell carcinoma associated antigen Human papilloma virus |
| 基金项目:国家自然科学基金(编号:81272881) |
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| 中文摘要: |
| 目的 探讨鳞状细胞相关抗原(SCCAg)、人类乳头状病毒分型检测(HPV)、液基细胞学检查(LCT) 与宫颈上皮内瘤样变Ⅲ级(CIN Ⅲ)患者宫颈锥切术后病理结果的相关性。 方法 回顾性分析105例CIN Ⅲ患者的病例资料,比较宫颈锥切术后病理高危组和低危组患者的术前SCCAg、HPV分型检测、LCT检查结果。 结果 宫颈锥切术后病理高危组血清SCCAg值高于低危组,差异有统计学意义(P<0.01);两组间HPV感染率和LCT阳性率比较,差异有统计学意义(P<0.05)。 结论 SCCAg值、LCT结果、HPV分型检测联合应用对确定宫颈锥切术后病理级别有指导意义。 |
| 英文摘要: |
| Objective To investigate the correlation between the pathological results of the patients with cervical intraepithelial neoplasia Ⅲ(CIN Ⅲ)after cold knife cervical conization and squamous cell carcinoma associated antigen(SCCAg), human papilloma virus DNA genotype(HPV), liquid-based cytology test (LCT). Methods A retrospective analysis of the clinical data was carried out in 105 cases with CIN Ⅲ. The pathological results after cold knife cervical conization were compared with preoperative SCCAg, HPV genotyping test, LCT between high-risk group and low-risk group. Results The levels of SCCAg in high-risk group were significantly higher than those in low-risk group(P<0.01). The positive rates of HPV infection and LCT in high-risk group and low-risk group were compared, and the difference between the two groups was significant(P<0.05). Conclusion The combined determination of SCCAg, HPV genotyping test and LCT is helpful in observing the pathological results after cold knife cervical conization. |
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