文章摘要
盐酸山莨菪碱配伍缩宫素对缩短产程的作用
Effect of anisodamine combined with oxytocin on shortening the birth process
投稿时间:2015-03-16  修订日期:2015-05-20
DOI:10.3969/j.issn.1000-0399.2015.08.023
中文关键词: 盐酸山莨菪碱  缩宫素  产程
英文关键词: Anisodamine  Oxytocin  Birth process
基金项目:
作者单位
杨志会 065400 河北省香河县妇幼保健院妇产科 
张艳梅 065400 河北省香河县妇幼保健院妇产科 
顾超 065400 河北省香河县妇幼保健院妇产科 
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中文摘要:
      目的 探讨盐酸山莨菪碱配伍缩宫素对缩短产程的作用。方法 将100例活跃期延长产妇随机分为两组,各50例。对照组在活跃期延长后单用缩宫素,观察组在此基础上联合使用盐酸山莨菪碱,比较两组产妇宫颈成熟度评分、产程时间、分娩方式、产后出血及新生儿情况。结果 观察组宫颈成熟度评分高于对照组,差异有统计学意义(P <0.05);自活跃期开始,观察组活跃期、第二产程、第三产程及总产程时间均短于对照组,差异有统计学意义(P <0.05);观察组剖宫产率为20.00%,低于对照组,差异有统计学意义(P <0.05);观察组产妇产后24 h出血量为(176.2±5.3) mL,低于对照组,差异有统计学意义(P <0.05);观察组新生儿出生后5 min Apgar评分为(9.3±0.5)分,高于对照组,差异有统计学意义(P <0.05)。结论 对活跃期延长的产妇应用盐酸山莨菪碱配伍缩宫素可加速宫口扩张,缩短产程,有利于改善产妇及新生儿预后。
英文摘要:
      Objective To investigate the effect of anisodamine combined with oxytocin on shortening the birth process. Methods 100 cases of maternals with prolonged active phase ever treated in our hospital were randomly divided into two groups, with 50 cases in each group. After the prolonged active phase was diagnosed, maternals in the study group were treated with anisodamine combined with oxytocin, whereas maternals in the control group treated with oxytocin alone. The maternal cervical maturity score, duration of labor, mode of delivery, postpartum hemorrhage and incidence of neonatal asphyxia between the two groups were compared. Results The maternal cervical maturity score in the study group was significantly higher than that in the control group (P <0.05). Duration of the active phase, the second labor stage, the third labor stage and the total labor stage in the study group were shorter than those in the control group, and the differences were statistically significant (P <0.01). The cesarean section rate of the study group was 20.00%, significantly lower than that of the control group (P <0.01), and the 24h postpartum hemorrhage of the study group was (176.2±5.3) ml, also significantly lower than that of the control group (P <0.01). But the 5 min Apgar score after birth of the study group was (9.3±0.6) points, significantly higher than that of the control group, with significant difference between the two groups (P <0.01). Conclusion Application of anisodamine combined with oxytocin for active phase prolonged maternals could accelerate cervical dilation and shorten birth process, as to improve maternal and neonatal outcomes, and should be widely promoted.
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