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| 中性粒细胞与淋巴细胞比率对NSTE-ACS患者左主干或三支病变的预测价值 |
| Predictive value of neutrophil-lymphocyte ratio for left main and/or three-vessel disease in patients with non ST-elevated acute coronary syndrome |
| 投稿时间：2015-08-08 |
| DOI：10.3969/j.issn.1000-0399.2016.03.015 |
| 中文关键词: 中性粒细胞与淋巴细胞比率 非ST段抬高型急性冠脉综合征 左主干或三支病变 |
| 英文关键词: Neutrophil-lymphocyte ratio Non ST-elevated acute coronary syndrome Left main and/or three-vessel disease |
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| 中文摘要: |
| 目的 探讨中性粒细胞与淋巴细胞比率(NLR)对非ST段抬高型急性冠脉综合征(NSTE-ACS)患者左主干或三支病变独立预测价值。方法 选取150例NSTE-ACS患者,根据冠脉造影结果分析NLR水平对NSTE-ACS患者左主干或三支病变的预测价值。结果 150例患者纳入最后的分析,通过受试者工作特征曲线分析,NLR水平预测NSTE-ACS患者左主干或三支病变的最佳截断值为2.58(曲线下面积0.72,特异性78.8%,敏感性61.2%)。150例NSTE-ACS患者中,NLR水平≥2.58的患者平均年龄较NLR<2.58的患者偏大(P=0.02),出现左主干或三支病变的比例明显升高(P<0.01)。logistic回归分析显示NLR≥2.58是对NSTE-ACS患者左主干或三支病变的独立预测因素(OR:4.73,95% CI:1.94~11.54,P<0.01)。结论 NLR≥2.58是预测NSTE-ACS患者左主干或三支病变的独立危险因素。 |
| 英文摘要: |
| Objective To evaluate the independent predictive value of neutrophil-lymphocyte ratio for LM/3VD in patients with non ST-elevated acute coronary syndrome.Methods A total of 150 NSTE-ACS patients were enrolled in this our study. The predictive value of neutrophil-lymphocyte ratio for LM/3VD in patients with NSTE-ACS was analysed according to the results of coronary angiography.Results All patients were included in the final analysis. By receiver operating characteristics curve analysis, the optimal cutoff value of NLR in predicting LM/3VD was 2.58(area under the curve 0.72, sensitivity 78.8%, specificity 61.2%). Of the 150 cases, patients who had NLR≥2.58. Patients were older(P=0.02) than patients with NLR<2.58 and had a higher prevalence of LM/3VD(P<0.01). According to multivariate logistic regression analysis, NLR≥2.58 was an independent predictor of LM/3VD(odds ratio 4.73, 95% confidence interval 1.94~11.54, P<0.01).Conclusion NLR≥2.58 is an independent predictor of LM/3VD for patients with NSTE-ACS. |
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