| Objective Observation of three dimensional conformal radiotherapy(3D-CRT) combined with cytokine induced killer(CIK) for clinical efficacy of primary liver cancer patients in advanced stage.Methods In our hospital from August 2013 to August 2015 in cancer center for treatment of 72 cases of advanced primary liver cancer,patients were divided into control group and observation group, 36 patients in each group.Observation group was treated with CIK for 2 times within 3 months after receiving 3D-CRT.3 months after treatment, Comprehensive analysis of the efficacy of 3D-CRT combined with CIK for the treatment of advanced PLC,according to liver CT, alpha fetal protein(AFP), Karnofsky and the change of immune function of the patients treated by flow cytometry.Results After treatment,in the two groups of tumor diameter and AFP change in data, the observation group[(4.17±1.65) cm and(348.5±127.2) ng/mL] was significantly better than the control group[(5.32±1.63) cm and(464.9±134.8) ng/mL,P<0.05].The surface markers of T cells and NK cells in the observation group were more than those of the control group(P<0.05).Conclusion In the treatment of advanced PLC, 3D-CRT combined with CIK therapy can improve the disease control rate(DCR), enhance the immunity of the body, and it is feasible and can be further discussed. |
