| Objective To study the factors affecting prognosis of pT4aN0M0 period gastric cancerfor providing a reference for cancer prevention. Methods A retrospective analysiswas performed on the clinical data of 57 patientswith postoperative pathologic stage pT4aN0M0 and who underwent radical surgery from January 2009 to January 2011, the five-year survival rate was calculated and comparedusing univariate and multivariate. Results pT4aN0M0 gastric cancer patients aged more than 60 years, there were more men than women, BMI was mostly less than 24 kg/m2, and the tumor sites were located in the upper part; tumor size was larger than 5 cm, negative lymph node number was more than 15, and adjuvant chemotherapy, tumor differentiation and prognosis of pT4aN0M0 gastric cancer were relevant. Meanwhile, gender, age, BMI and prognosis of pT4aN0M0 gastric cancer showed no relevance,and COX multivariate analysis showed that tumor size, number of lymph node-negative, adjuvant chemotherapy, tumor differentiation were the independent risk factors affecting the prognosis. Conclusion Tumor size, lymph node-negative number, adjuvant chemotherapy, tumor differentiation may be associated with the prognosis of pT4aN0M0 gastric cancer. |
