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| 非ST段抬高急性冠脉综合征合并H型高血压患者的预后分析 |
| A prognosis of patients with non-ST-segment elevation acute coronary syndrome combined with H-type hypertension |
| 投稿时间：2016-07-03 |
| DOI：10.3969/j.issn.1000-0399.2017.02.013 |
| 中文关键词: H型高血压 急性冠脉综合征 预后 B型脑钠肽 全球急性冠脉注册事件 |
| 英文关键词: H-type hypertension Acute coronary syndrome Prognosis B-type natriuretic peptide Global registry of acute coronary events |
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| 中文摘要: |
| 目的 探讨非ST段抬高急性冠脉综合征合并H型高血压患者的临床预后。方法 选取2014年11月至2015年12月安徽省淮北市中医院收治的非ST段抬高急性冠脉综合征合并原发性高血压患者123例，根据患者同型半胱氨酸（Hcy）水平将患者分成H型高血压组（Hcy≥10 μmmol/L）55例及对照组（Hcy<10 μmmol/L）68例。比较两组患者入院后2 h内B型脑钠肽和全球急性冠脉注册事件评分危险分层。结果 H型高血压组患者入院后2 h内血浆B型脑钠肽水平[（1 489.52±448.37）ng/L]较对照组[（950.45±310.62）ng/L]高，差异有统计学意义（t=7.858，P<0.001）；H型高血压组患者全球急性冠脉注册事件评分危险度高的比例较对照组高，危险度中的比例较对照组低，差异均有统计学意义（χ2=6.897、4.125，P=0.009、0.042）。结论 非ST段抬高急性冠脉综合征合并H型高血压患者临床预后较差 |
| 英文摘要: |
| Objective To explore the clinical prognosis of patients with non-ST-segment elevation acute coronary syndrome (ACR) combined with H-type hypertension.Methods From Nov 2014 to Dec 2015, 123 patients with non-ST-segment elevation ACR combined with primary hypertension, ever treated in our hospital, were selected and divided into the H-type hypertension group (Hcy≥10 mmol/L, 55 cases) and the control group (Hcy < 10 mmol/L, 68 cases) according to their homocysteine (Hcy) levels. The levels of B-type natriuretic peptide (BNP) within 2 hours after admission and the risk stratification of scores of global registry of acute coronary events (GRACE) in the patients of both groups were compared. Results In comparison with the control group, the H-type hypertension group had higher blood BNP levels within 2 hours after admission (1489.52±448.37 ng/L vs 950.45±310.62 ng/L), and the difference between them was statistically significant (t=7.858, P<0.001). Patients in the H-type hypertension group had higher proportion of high risk scores of GRACE (χ2=6.897, P=0.009) and lower proportion of moderate risk scores of GRACE (χ2=4.125, P=0.042). Conclusion The clinical prognosis of patients with non-ST-segment elevation ACS combined with H-type hypertension might be poor. |
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