文章摘要
小龙虾相关横纹肌溶解综合征90例临床分析
Rhabdomyolysis after cooked crayfish consumption: clinical analysis of 90 cases
投稿时间:2016-12-20  
DOI:10.3969/j.issn.1000-0399.2017.05.019
中文关键词: 横纹肌溶解综合征  小龙虾  哈夫病  并发症  治疗
英文关键词: Rhabdomyolysis  Crayfish  Haff disease  Complication  Therapeutic regimens
基金项目:
作者单位
唐晓飞 243000 马鞍山市人民医院肾内科 
沈馨茹 243000 马鞍山市人民医院内分泌科 
钱光荣 243000 马鞍山市人民医院肾内科 
李瑾 243000 马鞍山市人民医院肾内科 
摘要点击次数: 2016
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中文摘要:
      目的 探讨小龙虾相关横纹肌溶解综合征(RM)患者的临床特点、治疗和预后。方法 收集2016年6~8月马鞍山市人民医院收治的90例进食小龙虾后发生RM的患者资料,观察分析流行病学特点、临床表现、实验室指标如肌酶、尿常规、肾功能、电解质等变化情况、治疗措施及预后。结果 所有患者发病前24 h内均有食用小龙虾史,表现为全身性或局部肌肉疼痛,但均无发热、呕吐、四肢抽搐,实验室检查肌酸激酶(CK)、天门冬氨酸氨基转移酶(AST)、乳酸脱氢酶(LDH)和肌红蛋白(Mb)均明显高于正常值,但男女分组检验CK、Mb、AST、LDH等指标,差异均无统计学意义(P均>0.05),给予补液、碱化尿液等治疗,患者均未发生急性肾损伤,无死亡病例。结论 小龙虾相关RM是一种以肌肉疼痛为主要症状,严重并发症少的横纹肌溶解症,通过补液、碱化尿液等治疗,预后良好。
英文摘要:
      Objective To discuss the clinical features, therapeutic regimens and prognosis of rhabdomyolysis after cooked crayfish consumption. Methods Epidemiological characteristics, clinical manifestations, laboratory indexes including serum creatinase, urinalysis, renal function and electrolyte, therapeutic regimens and prognosis were recorded in 90 patients, who were admitted to the hospital of from June to August in 2016. Results All patients have eaten crayfish within 24 hours before the onset of illness. The patients all presented myalgia of whole or local body, but without fever, vomiting and limbs twitch. Laboratory examination showed obviously higher than normal level of creatine kinase(CK), aspartate aminotransferase(AST), lactic dehydrogenase(LDH) and myoglobin(Mb). However, there was no significant difference between the male and the female groups in serum levels of CK, Mb,AST and LDH(P>0.05). Through therapeutic regimens including volume repletion, alkalization of urine, no patient developed acute renal failure, and all patients recovered. Conclusion Rhabdomyolysis after cooked crayfish consumption is a syndrome of less severe complications, and the main symptom is myalgia and muscle stiffness, however, the prognosis is good.
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