| Objective To investigate the prognosis of different pathological types of left and right colon cancer. Methods A total of 386 patients with colon cancer in Dongguan People's Hospital from Jan 2005 to Dec 2010 were divided into group A (low/undifferentiated adenocarcinoma and mucinous adenocarcinoma and ring cell carcinoma, 152 cases) and group B(high/middle differentiated adenocarcinoma, 234 cases); meanwhile, according to the location of the tumor, the patients were divided into group of right side colon cancer and left side colon cancer. Then the relationship between different clinical pathological types and location and prognosis of patients were analysed. Results The TNM stage, T stage, N stage and serum CEA level were significantly higher in group A than those in group B (P<0.05). Type A was more common in right colon cancer (P<0.05). The five year survival rate of patients in group A was 52.43%, which was lower than that in group B 55.77% (P<0.05). The five year survival rate of patients with right colon cancer(53.66%) was lower than that in patients with left colon cancer(55.24%)(P<0.05). In group A, the five year survival rate of right colon cancer was higher than that of left colon cancer (52.82% vs 50.71%,P<0.05), while in group B, there was no difference between them(56.14% vs 54.27%,P>0.05). Conclusion In the low differentiated adenocarcinoma/mucinous carcinoma/signet ring cell carcinoma, the prognosis of right colon cancer is better than left colon cancer; however, the trend is opposite in the high/middle differentiated adenocarcinoma. |
