文章摘要
多模态磁共振成像在乳腺癌诊断中的应用价值
Application value of multi-modality magnetic resonance imaging in diagnosis of breast cancer
投稿时间:2017-03-28  
DOI:10.3969/j.issn.1000-0399.2017.08.002
中文关键词: 乳腺癌  弥散加权成像  动态增强磁共振  多模态磁共振成像
英文关键词: Breast cancer  Diffusion weighted imaging  Dynamic contrast-enhanced MRI  multi-modality MRI
基金项目:国家自然科学基金(项目编号:81171326)
作者单位E-mail
吴津民 230022 合肥 安徽医科大学第一附属医院放射科  
王海宝 230022 合肥 安徽医科大学第一附属医院放射科 wanghaibao916@163.com 
徐丽艳 230022 合肥 安徽医科大学第一附属医院放射科  
李仁民 230022 合肥 安徽医科大学第一附属医院放射科  
刘灿 230022 合肥 安徽医科大学第一附属医院放射科  
马宁 230022 合肥 安徽医科大学第一附属医院放射科  
鲁学婷 230022 合肥 安徽医科大学第一附属医院放射科  
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中文摘要:
      目的 应用多模态MRI包括弥散加权成像和动态增强扫描(DCE-MRI)对乳腺癌患者的检测,分析其MRI相关影像特征,探讨其对该病诊断的准确性。方法 回顾分析2012年1月至2016年8月于安徽医科大学第一附属医院术前行MRI检查和术后病理或穿刺活检证实的16例乳腺癌女性患者多模态MRI数据资料,统计分析表观弥散系数(ADC)、相对表观弥散系数(rADC)值及动态时间信号强度曲线图像(TIC)。结果 16例患者MRI显示病灶多见分叶(75.00%)、毛刺(75.00%),边界不清(81.25%)。ADC值为(0.92±0.19)×10-3 mm2/s,rADC为(0.56±0.13)×10-3 mm2/s。TIC:Ⅱ型4例(25.00%),Ⅲ型12例(75.00%),无符合Ⅰ型的病例。结论 多模态MRI用于乳腺癌的检查,结合病变形态学改变、DCE-MRI的TIC曲线形态和ADC值,可以提高乳腺癌的诊断正确率。
英文摘要:
      Objective To further improve the diagnostic accuracy of breast cancer by application of multi-modality MRI, including diffusion-weighted imaging (DWI) and dynamic contrast-enhanced (DCE) scanning, in the detection of patients with breast cancer and the analysis of characteristics of the MRI images. Methods The multi-modality MRI data of 16 female patients with breast cancer, diagnosed by preoperative MRI and postoperative pathological examination or biopsy in our hospital from Jan 2012 to Aug 2016, were retrospectively analyzed. Values of apparent diffusion coefficient (ADC) and relative apparent diffusion coefficient (rADC) were calculated, and dynamic time-signal intensity curve (TIC) was constructed. Results In the MRI images of 16 patients, lesions often tended to be lobulated, spiculated (75.0%) and ill-defined. Their ADC and rADC values were (0.92±0.19)×10-3 mm2/s and (0.56±0.13)×10-3 mm2/s, respectively. As for TIC, 4 cases of type Ⅱ (25.0%) and 12 cases of type Ⅲ (75.0%) were found, with no case of type I. Conclusion When applied in detection of breast cancer, multi-modality MRI, combining with morphological change of lesions, TIC curve of DCE-MRI and ADC value, may improve the diagnostic accuracy of breast cancer.
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