Objective To discuss the prediction value of mid pregnancy pre-body mass index, serological screening and glucose tolerance test for preeclampsia. Methods The clinical data of 1496 cases of pregnant women admitted to the Department of Gynaecology and Obstetrics in our hospital between December 2014 and September 2014 were collected. 177 cases of pregnant women who suffered PE were recruited in PE group, and another 177 cases of normal pregnancy were randomly matched as control group, then a comparative analysis was performed on two groups of pregnant women; screening test was carried out for the data of all pregnant women, and the evaluation was conducted for the value of the selected index in the single and combined forecast of PE. Results There was no statistical difference in the age of two groups of pregnant women (P>0.05). Pre-pregnancy BMI, hCG, AFP, uE3 and OGTT data had statistically significant difference(P<0.05). Pre-pregnancy BMI, hCG, OGTT had predictive value of PE (AUC>0.5); however, AFP, uE3 had no predictive value of PE (AUC<0.5). When pre-pregnancy BMI, hCG, 2 h-Glu were combined in the forecast of PE, the AUC=0.79, sensitivity was 78.41%, and specificity was 73.38%. Conclusion Joint indicators from different sources can improve the predictive value of preeclampsia. |