文章摘要
结直肠癌患者术前血小板计数水平与肿瘤临床病理分期的关系
Association of platelet count and clinicopathological characteristics in colorectal cancer
投稿时间:2017-06-23  
DOI:10.3969/j.issn.1000-0399.2017.12.007
中文关键词: 结直肠癌  临床病理特征  血小板增多症
英文关键词: Colorectal cancer  Clinicopathological characteristics  Thrombocytosis
基金项目:
作者单位
张俊 230031 合肥 安徽省肿瘤医院(安徽省立医院西区)胃肠外科 
宁忠良 230031 合肥 安徽省肿瘤医院(安徽省立医院西区)胃肠外科 
赵旭辉 230031 合肥 安徽省肿瘤医院(安徽省立医院西区)胃肠外科 
魏忠 230031 合肥 安徽省肿瘤医院(安徽省立医院西区)胃肠外科 
樊平 230031 合肥 安徽省肿瘤医院(安徽省立医院西区)胃肠外科 
戴寅 230031 合肥 安徽省肿瘤医院(安徽省立医院西区)胃肠外科 
谢钊 230031 合肥 安徽省肿瘤医院(安徽省立医院西区)胃肠外科 
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中文摘要:
      目的 探讨结直肠癌患者术前血小板计数水平与肿瘤临床病理分期的关系。方法 回顾性分析2015年1月至2016年12月安徽省肿瘤医院胃肠外科经组织病理学确诊的420例结直肠癌患者的临床资料,统计不同临床分期结直肠癌患者血小板增多症的发生率。结果 结直肠癌血小板增多症发生率与肿瘤分化程度、淋巴转移、性别、年龄、肿瘤部位均无密切关系(P>0.05)。初诊时发现血小板增多症70例(16.67%),术后TNM I期70例,Ⅱ期99例,Ⅲ期217例,Ⅳ期34例,血小板增多症发生率依次为7.14%、14.14%、18.89%和29.41%,差异有统计学意义(P<0.05)。结论 结直肠癌患者临床病理分期与血小板增多有密切关系。
英文摘要:
      Objective To explore the relationship between platelet count and colorectal cancer at the points of clinicatholocal stageand the prognosis.Methods The clinical data of 420 colorectal cancer patients from January 2015 to December 2016 were retrospectively analyzed. The frequency of patients with thrombocytosis in different clinicopathological stages was analyzed.Results Platelet count was associated with histological grade, distant metastasis, type, invasion depth and tumor stage (P<0.05), but not with degree of differentiation, lymph node metastasis, gender, age and tumor location(P>0.05). 16.67% patients with colorectal cancer were accompanied with thrombocytosis. The frequency of patients with thrombocytosis in I(70 cases), Ⅱ(99 cases), Ⅲ(217 cases), IV stage(34 cases) were 7.14%,14.14%,18.89%,29.41%, respectively and the difference was statistically significant(P<0.05).Conclusion There is a close relationship between platelet count and colorectal cancer.
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