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| 腹膜透析患者肾结石发病情况及危险因素分析 |
| Prevalence and risk factors of kidney stones in patients on peritoneal dialysis |
| 投稿时间：2017-08-10 |
| DOI：10.3969/j.issn.1000-0399.2018.01.005 |
| 中文关键词: 腹膜透析 肾结石 危险因素 |
| 英文关键词: Peritoneal dialysis Kidney stone Risk factor |
| 基金项目:安徽高校自然科学研究重点项目（项目编号：KJ2016A343） |
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| 中文摘要: |
| 目的 调查腹膜透析患者与普通人群肾结石的发病情况，并探讨腹膜透析患者发生肾结石的危险因素。方法 以安徽医科大学第一附属医院肾内科2015年7月至2017年7月随访的107例腹膜透析患者为研究对象（腹透组），分析腹透组患者肾结石的患病情况，并与普通人群肾结石患病率进行比较。再将腹透组患者分为结石组和非结石组，检测两组患者血红蛋白、清蛋白、球蛋白、尿素氮、肌酐、尿酸、钙、磷等生化指标，并记录两组患者的透析时间及尿量。结果 规律腹膜透析患者肾结石的患病率为21.5%，高于本地区普通人群肾结石患病率（4.8%），差异有统计学意义（P<0.05）。结石组的尿酸及胆固醇水平高于非结石组，差异有统计学意义（P<0.05）。logistic回归分析显示，腹膜透析患者肾结石危险因素包括男性、高尿酸血症及高脂血症。结论 腹膜透析患者肾结石的患病率高于普通人群，男性、高尿酸血症、高脂血症是其肾结石形成的独立危险因素。 |
| 英文摘要: |
| Objective To investigate whether the prevalence of kidney stones in peritoneal dialysis patients was higher than that in the general population and to explore the possible causes.Methods We analyzed the prevalence of kidney stones in 107 peritoneal dialysis patients followed up in our hospital from July 2015 to July 2017. And we compared it with the general population.Peritoneal dialysis patients were divided into stone group and non-stone group, and the clinical and laboratory indexes of the two groups were assessed. Results The prevalence of kidney stones in peritoneal dialysis patients followed up in our hospital was 21.5%, which was higher than in the general population, and the difference was statistically significant. Logistic regression analysis showed that male, hyperuricemia and hyperlipidemia were risk factors for kidney stones in peritoneal dialysis patients. Conclusion The prevalence of kidney stones in peritoneal dialysis patients is higher than that in the general population. The risk factors of kidney stones in peritoneal dialysis patients are men, hyperuricemia and hyperlipidemia. |
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